Sorafenib Dosing Nomogram
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Section editor transclusions This page contains studies that were specific to pediatric populations. For the more general AML page, follow this link.
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AAML1031 Sorafenib Dosing Nomogram=
| BSA Range (m2) | Dose Level 0 (100 mg/m2/day once daily) | Dose Level 1 (200 mg/m2/day once daily) | Dose Level 2 (300 mg/m2/day divided BID) |
|---|---|---|---|
| ≤ 0.35 | 50 mg x 4 days/week,
0 x 3 day/week (200 mg) |
50 mg x 5 days/week,
100 mg x 2 days/week (450 mg) |
50 mg twice daily x 7 days/week
(700 mg) |
| 0.36 - 0.4 | 50 mg x 5 days/week,
0 x 2 day/week (250 mg) |
50 mg x 4 days/week,
100 mg x 3 days/week (500 mg) |
50 mg twice daily x 6 days/week +
100 mg twice daily x 1 day/week (800 mg) |