Vadimezan (AS-A404)
Revision as of 13:50, 23 September 2023 by Warner-admin (talk | contribs) (Text replacement - "analogue" to "analog")
Mechanism of action
From the NCI Drug Dictionary: A fused tricyclic analog of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiogenesis. This agent also stimulates the anti-tumor activity of tumor-associated macrophages.
Also known as
- Code names: AS-1404, AS-A404