Avatrombopag (Doptelet)

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Mechanism of action

Thrombopoietin receptor agonist

Preliminary data

Autoimmune thrombocytopenic purpura (ITP)

Randomized Phase II, >20 per arm

  1. Bussel JB, Kuter DJ, Aledort LM, Kessler CM, Cuker A, Pendergrass KB, Tang S, McIntosh J. A randomized trial of avatrombopag, an investigational thrombopoietin-receptor agonist, in persistent and chronic immune thrombocytopenia. Blood. 2014 Jun 19;123(25):3887-94. Epub 2014 May 6. link to original article PubMed

Also known as

YM477, AKR 501

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