Blastic plasmacytoid dendritic cell neoplasm
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Section editor | |
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Martin W. Schoen, MD, MPH Saint Louis University St. Louis, MO ![]() |
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1 variants on this page
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All lines of therapy
Tagraxofusp monotherapy
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Regimen
Study | Evidence |
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Frankel et al. 2014 | Phase I/II, <20 pts |
Chemotherapy
- Tagraxofusp (Elzonris) 12 mcg/kg IV over 15 minutes once per day on days 1 to 5
21-day cycles
References
- Frankel AE, Woo JH, Ahn C, Pemmaraju N, Medeiros BC, Carraway HE, Frankfurt O, Forman SJ, Yang XA, Konopleva M, Garnache-Ottou F, Angelot-Delettre F, Brooks C, Szarek M, Rowinsky E. Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients. Blood. 2014 Jul 17;124(3):385-92. Epub 2014 May 23. link to original article PubMed