Difference between revisions of "Pentraxin 2 (PRM-151)"
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(Created page with "==General information== Class/mechanism per [http://www.cancer.gov/publications/dictionaries/cancer-drug?CdrID=753252 NCI Drug Dictionary]: A fully recombinant form of the hum...") |
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==General information== | ==General information== | ||
| − | Class/mechanism per [http://www.cancer.gov/publications/dictionaries/cancer-drug?CdrID= | + | Class/mechanism per [http://www.cancer.gov/publications/dictionaries/cancer-drug?CdrID=755555 NCI Drug Dictionary]: A fully recombinant form of the human pentraxin 2 (PTX2) protein with potential antifibrotic activity. Upon intravenous administration, recombinant human serum amyloid P/pentraxin 2 (PRM-151) may inhibit myofibroblast generation by preventing the differentiation of circulating monocytes into fibrocytes and profibrotic macrophages. PTX2 is a circulating plasma protein that belongs to the class of pattern recognition receptors (PRR) of the innate immune system. |
<br>Route: IV | <br>Route: IV | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
Revision as of 14:49, 17 September 2015
General information
Class/mechanism per NCI Drug Dictionary: A fully recombinant form of the human pentraxin 2 (PTX2) protein with potential antifibrotic activity. Upon intravenous administration, recombinant human serum amyloid P/pentraxin 2 (PRM-151) may inhibit myofibroblast generation by preventing the differentiation of circulating monocytes into fibrocytes and profibrotic macrophages. PTX2 is a circulating plasma protein that belongs to the class of pattern recognition receptors (PRR) of the innate immune system.
Route: IV
Extravasation: n/a