Difference between revisions of "Anastrozole (Arimidex)"
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==General information== | ==General information== | ||
| − | Class/mechanism: Selective non-steroidal aromatase inhibitor.<ref name="insert">[http://www1.astrazeneca-us.com/pi/arimidex.pdf Anastrozole (Arimidex) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/anastrozole.pdf Anastrozole (Arimidex) package insert (locally hosted backup)]</ref> | + | Class/mechanism: Selective non-steroidal aromatase inhibitor. The aromatase enzyme converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.<ref name="insert">[http://www1.astrazeneca-us.com/pi/arimidex.pdf Anastrozole (Arimidex) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/anastrozole.pdf Anastrozole (Arimidex) package insert (locally hosted backup)]</ref> |
<br>Route: PO | <br>Route: PO | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
Revision as of 04:05, 14 January 2012
General information
Class/mechanism: Selective non-steroidal aromatase inhibitor. The aromatase enzyme converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.[1][2]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Anastrozole (Arimidex) patient drug information (Chemocare)[3]
- Anastrozole (Arimidex) patient drug information (UpToDate)[4]
Regimen
Anastrozole (Arimidex) 1mg PO daily (adjuvant, locally advanced, metastatic breast cancer)