Difference between revisions of "Pentraxin 2 (PRM-151)"
Jump to navigation
Jump to search
m |
m |
||
| Line 7: | Line 7: | ||
===[[Myelofibrosis]]=== | ===[[Myelofibrosis]]=== | ||
| + | |||
| + | ==Also known as== | ||
| + | *'''Code name:''' PRM-151 | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 17:49, 15 April 2021
General information
Class/mechanism per NCI Drug Dictionary: A fully recombinant form of the human pentraxin 2 (PTX2) protein with potential antifibrotic activity. Upon intravenous administration, recombinant human serum amyloid P/pentraxin 2 (PRM-151) may inhibit myofibroblast generation by preventing the differentiation of circulating monocytes into fibrocytes and profibrotic macrophages. PTX2 is a circulating plasma protein that belongs to the class of pattern recognition receptors (PRR) of the innate immune system.
Route: IV
Extravasation: n/a
Preliminary data
Myelofibrosis
Also known as
- Code name: PRM-151