Difference between revisions of "Vincristine (Oncovin)"

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For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref>  
 
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref>  
 
==Diseases for which it is used==
 
*[[Acute lymphocytic leukemia]]
 
*[[Aggressive Non-Hodgkin lymphoma]]
 
*[[Bone cancer]]
 
*[[Central nervous system (CNS) cancer]]
 
*[[Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL)]]
 
*[[Follicular lymphoma]]
 
*[[HIV-associated lymphoma]]
 
*[[Hodgkin lymphoma]]
 
*[[Hodgkin lymphoma, nodular lymphocyte-predominant]]
 
*[[Mantle cell lymphoma]]
 
*[[Multiple myeloma]]
 
*[[Neuroendocrine tumors]]
 
*[[Penile cancer]]
 
*[[Sarcoma]]
 
*[[Small cell lung cancer]]
 
*[[Thymoma]]
 
*[[Transplant conditioning regimens]]
 
  
 
==Patient drug information==
 
==Patient drug information==
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[[Category:Microtubule inhibitors]]
 
[[Category:Microtubule inhibitors]]
 
[[Category:Vinca alkaloids]]
 
[[Category:Vinca alkaloids]]
 +
 +
[[Category:Acute lymphocytic leukemia medications]]
 +
[[Category:Aggressive Non-Hodgkin lymphoma medications]]
 +
[[Category:Bone cancer medications]]
 +
[[Category:Central nervous system (CNS) cancer medications]]
 +
[[Category:Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL) medications]]
 +
[[Category:Follicular lymphoma medications]]
 +
[[Category:HIV-associated lymphoma medications]]
 +
[[Category:Hodgkin lymphoma medications]]
 +
[[Category:Hodgkin lymphoma, nodular lymphocyte-predominant medications]]
 +
[[Category:Mantle cell lymphoma medications]]
 +
[[Category:Multiple myeloma medications]]
 +
[[Category:Neuroendocrine tumor medications]]
 +
[[Category:Penile cancer medications]]
 +
[[Category:Sarcoma medications]]
 +
[[Category:Small cell lung cancer medications]]
 +
[[Category:T-cell lymphoma medications]]
 +
[[Category:Thymoma medications]]
 +
[[Category:Transplant medications]]

Revision as of 19:19, 11 June 2014

General information

Class/mechanism: Vinca alkaloid, inhibits microtubule formation in the mitotic spindle, causing cell cycle arrest in metaphase.[1][2]
Route: IV
Extravasation: vesicant

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Patient drug information

Also known as

Precise Name: vinCRIStine Sulfate (RXCUI 11203)

Synonyms
Alcrist Biocrist Biocrystin Cellcristin Citomid Citomid RU Crivosin Cytomid
Farmistin CS Fauldvincri Krebin Kyocristine Nevexitin Oncocristin AQ Oncovin ELI Lilly Oncovin INJ.LSG.
Oncovin Yamakawa Onkocristin P&U Vincristine Pericristine Pharmacristine Tecnocris Trav Vincristine Vero Vincristin
Vincasar Vincasar PFS Vinces Vincosid Vincran Vincrex Vincrifil Vincrin
Vincrisin Vincrisol Vincristin Vincristina Vincristina Faulding Vincristina Filaxis Vincristina Martian Vincristin Biosyn
Vincristin CS Vincristine Vincristine Abic Vincristine Comp Vincristine DBL Vincristine Lederle Vincristine Mayne Vincristine Mayne Pharma ( BEN )
Vincristine Pharmachemie Vincristinesulfaat Vincristine Sulfate Vincristine Sulfate Synthelabo Vincristine Sulp Vincristine Sulphate Vincristine Teva Vincristinsulfat
Vincristin Sulfate Vincristinum Vincrisul Vinracin Vinracine Vinstin Vintec

References