Difference between revisions of "Warm autoimmune hemolytic anemia"

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m (Jwarner moved page Autoimmune hemolytic anemia to Warm autoimmune hemolytic anemia: More accurate)
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There is significant overlap between this and the '''[[autoimmune cytopenias]]''' page; please check there for a relevant regimen.
 
 
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=All lines of therapy=
 
=All lines of therapy=
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To be completed
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[[Category:Autoimmune hemolytic anemia regimens]]
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==Prednisolone monotherapy {{#subobject:5f27f2|Regimen=1}}==
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|[[#top|back to top]]
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===Regimen {{#subobject:d3c7eb|Variant=1}}===
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{| class="wikitable" style="width: 100%; text-align:center;"
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! style="width: 25%" |Study
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! style="width: 25%" |[[Levels_of_Evidence#Evidence|Evidence]]
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! style="width: 25%" |Comparator
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! style="width: 25%" |[[Levels_of_Evidence#Efficacy|Efficacy]]
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|[https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.12541 Birgens et al. 2013]
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| style="background-color:#1a9851" |Phase III (C)
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|[[#Prednisolone_.26_Rituximab|Prednisolone & Rituximab]]
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| style="background-color:#fc8d59" |Seems to have inferior RFS
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====Immunosuppressive therapy====
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*[[Prednisolone (Millipred)]]
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===References===
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# Birgens H, Frederiksen H, Hasselbalch HC, Rasmussen IH, Nielsen OJ, Kjeldsen L, Larsen H, Mourits-Andersen T, Plesner T, Rønnov-Jessen D, Vestergaard H, Klausen TW, Schöllkopf C. A phase III randomized trial comparing glucocorticoid monotherapy versus glucocorticoid and rituximab in patients with autoimmune haemolytic anaemia. Br J Haematol. 2013 Nov;163(3):393-9. Epub 2013 Aug 24. [https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.12541 link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/23981017 PubMed]
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==Prednisolone & Rituximab {{#subobject:598gf2|Regimen=1}}==
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{| class="wikitable" style="float:right; margin-left: 5px;"
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|[[#top|back to top]]
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===Regimen {{#subobject:a7c7eb|Variant=1}}===
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{| class="wikitable" style="width: 100%; text-align:center;"
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! style="width: 25%" |Study
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! style="width: 25%" |[[Levels_of_Evidence#Evidence|Evidence]]
 +
! style="width: 25%" |Comparator
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! style="width: 25%" |[[Levels_of_Evidence#Efficacy|Efficacy]]
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|-
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|[https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.12541 Birgens et al. 2013]
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| style="background-color:#1a9851" |Phase III (E)
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|[[#Prednisolone_monotherapy|Prednisolone]]
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| style="background-color:#91cf60" |Seems to have superior RFS
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|}
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====Immunosuppressive therapy====
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*[[Prednisolone (Millipred)]]
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*[[Rituximab (Rituxan)]]
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===References===
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# Birgens H, Frederiksen H, Hasselbalch HC, Rasmussen IH, Nielsen OJ, Kjeldsen L, Larsen H, Mourits-Andersen T, Plesner T, Rønnov-Jessen D, Vestergaard H, Klausen TW, Schöllkopf C. A phase III randomized trial comparing glucocorticoid monotherapy versus glucocorticoid and rituximab in patients with autoimmune haemolytic anaemia. Br J Haematol. 2013 Nov;163(3):393-9. Epub 2013 Aug 24. [https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.12541 link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/23981017 PubMed]
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[[Category:Warm autoimmune hemolytic anemia regimens]]
 
[[Category:Disease-specific pages]]
 
[[Category:Disease-specific pages]]
 
[[Category:Autoimmune hematologic conditions]]
 
[[Category:Autoimmune hematologic conditions]]
 
[[Category:Hemolytic process]]
 
[[Category:Hemolytic process]]

Revision as of 14:09, 1 October 2019

Section editor
Tillman Benjamin-2.jpg
 Benjamin Tillman, MD
Vanderbilt University
Nashville, TN
4 regimens on this page
3 variants on this page


Guidelines

British Society for Haematology

All lines of therapy

Prednisolone monotherapy

back to top

Regimen

Study Evidence Comparator Efficacy
Birgens et al. 2013 Phase III (C) Prednisolone & Rituximab Seems to have inferior RFS

Immunosuppressive therapy

References

  1. Birgens H, Frederiksen H, Hasselbalch HC, Rasmussen IH, Nielsen OJ, Kjeldsen L, Larsen H, Mourits-Andersen T, Plesner T, Rønnov-Jessen D, Vestergaard H, Klausen TW, Schöllkopf C. A phase III randomized trial comparing glucocorticoid monotherapy versus glucocorticoid and rituximab in patients with autoimmune haemolytic anaemia. Br J Haematol. 2013 Nov;163(3):393-9. Epub 2013 Aug 24. link to original article PubMed

Prednisolone & Rituximab

back to top

Regimen

Study Evidence Comparator Efficacy
Birgens et al. 2013 Phase III (E) Prednisolone Seems to have superior RFS

Immunosuppressive therapy

References

  1. Birgens H, Frederiksen H, Hasselbalch HC, Rasmussen IH, Nielsen OJ, Kjeldsen L, Larsen H, Mourits-Andersen T, Plesner T, Rønnov-Jessen D, Vestergaard H, Klausen TW, Schöllkopf C. A phase III randomized trial comparing glucocorticoid monotherapy versus glucocorticoid and rituximab in patients with autoimmune haemolytic anaemia. Br J Haematol. 2013 Nov;163(3):393-9. Epub 2013 Aug 24. link to original article PubMed
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