Difference between revisions of "Anastrozole (Arimidex)"
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==General information== | ==General information== | ||
| − | Class/mechanism: Selective non-steroidal aromatase inhibitor. The aromatase enzyme converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.<ref name="insert">[http://www1.astrazeneca-us.com/pi/arimidex.pdf Anastrozole (Arimidex) package insert]</ref><ref>[ | + | Class/mechanism: Selective non-steroidal aromatase inhibitor. The aromatase enzyme converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.<ref name="insert">[http://www1.astrazeneca-us.com/pi/arimidex.pdf Anastrozole (Arimidex) package insert]</ref><ref>[[Media:Anastrozole.pdf | Anastrozole (Arimidex) package insert (locally hosted backup)]]</ref><ref>[http://www.arimidex.com/ Arimidex manufacturer's website]</ref> |
<br>Route: PO | <br>Route: PO | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | ||
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| + | ==Diseases for which it is used== | ||
| + | *[[Breast cancer]] | ||
| + | *[[Uterine cancer]] | ||
==Patient drug information== | ==Patient drug information== | ||
| + | *[http://www1.astrazeneca-us.com/pi/arimidex.pdf#page=10 Anastrozole (Arimidex) package insert PDF pages 10-11]<ref name="insert"></ref> | ||
*[http://chemocare.com/bio/anastrozole.asp Anastrozole (Arimidex) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/anastrozole.asp Anastrozole (Arimidex) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/bio/anastrozole.asp Anastrozole (Arimidex) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/anastrozole.asp Anastrozole (Arimidex) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/anastrozole-patient-drug-information Anastrozole (Arimidex) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/anastrozole-patient-drug-information Anastrozole (Arimidex) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/anastrozole-patient-drug-information Anastrozole (Arimidex) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/anastrozole-patient-drug-information Anastrozole (Arimidex) patient drug information (UpToDate)]</ref> | ||
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==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 15:47, 17 September 2012
General information
Class/mechanism: Selective non-steroidal aromatase inhibitor. The aromatase enzyme converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.[1][2][3]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Anastrozole (Arimidex) package insert PDF pages 10-11[1]
- Anastrozole (Arimidex) patient drug information (Chemocare)[4]
- Anastrozole (Arimidex) patient drug information (UpToDate)[5]