Difference between revisions of "Example orders for weekly 5-FU & Leucovorin in colon cancer"
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==Weekly 5-FU & Leucovorin== | ==Weekly 5-FU & Leucovorin== | ||
| − | Original | + | Original references may be found at [[Colon_cancer#Fluorouracil_.285-FU.29_.26_Folinic_acid_.28Leucovorin.29_2|weekly 5-FU & Leucovorin]] |
===Example regimen #1=== | ===Example regimen #1=== | ||
Revision as of 16:43, 3 July 2012
Use of this site is subject to you reading and agreeing with the terms set forth in the disclaimer.
Weekly 5-FU & Leucovorin
Original references may be found at weekly 5-FU & Leucovorin
Example regimen #1
- Folinic acid (Leucovorin) 20 mg/m2 IV over 2 hours on days 1, 8, 15, given first
- Fluorouracil (5-FU) 500 mg/m2 IV bolus on days 1, 8, 15, given 1 hour after start of leucovorin
28-day cycles
Supportive medications:
- Prochlorperazine (Compazine) 10 mg PO prn nausea
Hydration:
- 500 ml NS at KVO rate as running IV for chemotherapy infusion. Give up to 500 ml NS.
Monitoring:
- Hold if patient has significant diarrhea/mucositis, ANC <1000, or platelets <100 and notify physician.
Comments:
- My institution administers this regimen with a 3 weeks on, 1 week off schedule for every 28-day cycle.