Difference between revisions of "Aldesleukin (Proleukin)"
m (→References) |
m |
||
| Line 1: | Line 1: | ||
| − | |||
| − | |||
==General information== | ==General information== | ||
| − | Class/mechanism: Recombinant interleukin-2 which activates the immune system. Aldesleukin encourages growth of IL-2 dependent cells, triggers natural killer (NK) and lymphokine-activated killer (LAK) cell activity, induces production of interferon gamma, and increases lymphocyte cytotoxicity.<ref name="insert">[ | + | Class/mechanism: Recombinant interleukin-2 which activates the immune system. Aldesleukin encourages growth of IL-2 dependent cells, triggers natural killer (NK) and lymphokine-activated killer (LAK) cell activity, induces production of interferon gamma, and increases lymphocyte cytotoxicity.<ref name="insert">[https://www.proleukin.com/downloads/proleukin-pi.pdf Aldesleukin (Proleukin) package insert]</ref><ref>[[Media:Aldesleukin.pdf | Aldesleukin (Proleukin) package insert (locally hosted backup)]]</ref><ref>[http://www.proleukin.com/ Proleukin manufacturer's website]</ref> |
<br>Route: IV | <br>Route: IV | ||
<br>Extravasation: no information | <br>Extravasation: no information | ||
| Line 19: | Line 17: | ||
==History of changes in FDA indication== | ==History of changes in FDA indication== | ||
* 5/5/1992: Initial FDA approval | * 5/5/1992: Initial FDA approval | ||
| + | |||
| + | ==Also known as== | ||
| + | Interleukin-2, IL-2, or Macrolin. | ||
==References== | ==References== | ||
Revision as of 01:12, 21 May 2017
General information
Class/mechanism: Recombinant interleukin-2 which activates the immune system. Aldesleukin encourages growth of IL-2 dependent cells, triggers natural killer (NK) and lymphokine-activated killer (LAK) cell activity, induces production of interferon gamma, and increases lymphocyte cytotoxicity.[1][2][3]
Route: IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Aldesleukin (Proleukin) patient drug information (Chemocare)[4]
- Aldesleukin (Proleukin) patient drug information (UpToDate)[5]
History of changes in FDA indication
- 5/5/1992: Initial FDA approval
Also known as
Interleukin-2, IL-2, or Macrolin.