Difference between revisions of "Antithrombin III (human and recombinant)"
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(added info about both human and recombinant AT III) |
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| − | + | May be known as antithrombin (human), antithrombin (recombinant), ATryn, or Thrombate III. | |
==General information== | ==General information== | ||
| − | Class/mechanism: Inhibitor of thrombin, which converts fibrinogen to fibrin in the coagulation cascade and subsequent development of thrombus. Clinical applications include management of patients with hereditary antithrombin III (AT-III) deficiency.<ref name="insert">[http://www.talecris-pi.info/inserts/thrombate.pdf Antithrombin III (Thrombate III) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/antithrombiniii.pdf Antithrombin III (Thrombate III) package insert (locally hosted backup)]</ref><ref>[http:// | + | Class/mechanism: Inhibitor of thrombin, which converts fibrinogen to fibrin in the coagulation cascade and subsequent development of thrombus. Clinical applications include management of patients with hereditary antithrombin III (AT-III) deficiency. Please choose from the products below to find specific drug/manufacturer information: |
| − | < | + | *Antithrombin III, human (Thrombate III)<ref>[http://www.thrombate.com/ Thrombate III manufacturer's website]</ref><ref name="insert">[http://www.talecris-pi.info/inserts/thrombate.pdf Antithrombin III, human (Thrombate III) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/antithrombiniii.pdf Antithrombin III, human (Thrombate III) package insert (locally hosted backup)]</ref> |
| + | *Antithrombin III, recombinant (ATryn)<ref>[http://atryn.com/ ATryn manufacturer's website]</ref><ref>[http://atryn.com/pdf/ATryn_PI_0409.pdf Antithrombin III, recombinant (ATryn) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/antithrombiniiiatryn.pdf Antithrombin III, recombinant (ATryn) package insert (locally hosted backup)]</ref> | ||
| + | Route: IV | ||
<br>Extravasation: no information | <br>Extravasation: no information | ||
Revision as of 08:16, 17 March 2012
May be known as antithrombin (human), antithrombin (recombinant), ATryn, or Thrombate III.
General information
Class/mechanism: Inhibitor of thrombin, which converts fibrinogen to fibrin in the coagulation cascade and subsequent development of thrombus. Clinical applications include management of patients with hereditary antithrombin III (AT-III) deficiency. Please choose from the products below to find specific drug/manufacturer information:
Route: IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information[2].
Patient drug information
References
- ↑ Thrombate III manufacturer's website
- ↑ 2.0 2.1 Antithrombin III, human (Thrombate III) package insert
- ↑ Antithrombin III, human (Thrombate III) package insert (locally hosted backup)
- ↑ ATryn manufacturer's website
- ↑ Antithrombin III, recombinant (ATryn) package insert
- ↑ Antithrombin III, recombinant (ATryn) package insert (locally hosted backup)
- ↑ Antithrombin III (Thrombate III) patient drug information (UpToDate)