Difference between revisions of "Cisplatin (Platinol)"

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Template to be used for chemotherapies:
 
Template to be used for chemotherapies:
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(strive for minimalism, focus on regimens)
  
Mechanism
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==General information==
*Platinum analog, alkylating-like
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Class: Platinum analog, alkylating-like<ref name="insert">[http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018057s080lbl.pdf Cisplatin package insert (8/2011)]</ref>
*metabolism
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Extravasation: [[vesicant]]
*Excretion: renal ~90%, bile 10%
 
*CYP450: unknown
 
  
Dosing
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For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list additional information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>.
*Renal dose adjustments
 
*Hepatic dose adjustments
 
  
Routes of administration: IV
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==Consent==
*Vesicant?
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*Side effects discussed for informed consent*
*Antidote?
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*Patient information for informed consent (patient drug information sheet)
 
 
Side effects
 
*Patient information for informed consent
 
*patient drug information
 
  
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==Regimens==
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Standard format will be:
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<nowiki><acronym (if any)> (generic drug1, generic drug2, generic drug3, etc.) (disease)</nowiki>
 
[http://hemonc.org/index.php?title=Special:WhatLinksHere/Cisplatin_(Platinol) List of regimens containing cisplatin]
 
[http://hemonc.org/index.php?title=Special:WhatLinksHere/Cisplatin_(Platinol) List of regimens containing cisplatin]
  
 
==References==
 
==References==
[http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018057s080lbl.pdf Cisplatin package insert (8/2011)]
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<references/>

Revision as of 07:25, 13 November 2011

Template to be used for chemotherapies: (strive for minimalism, focus on regimens)

General information

Class: Platinum analog, alkylating-like[1] Extravasation: vesicant

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list additional information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].

Consent

  • Side effects discussed for informed consent*
  • Patient information for informed consent (patient drug information sheet)

Regimens

Standard format will be: <acronym (if any)> (generic drug1, generic drug2, generic drug3, etc.) (disease) List of regimens containing cisplatin

References