Difference between revisions of "CARv3-TEAM-E T-cells"

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==Preliminary data==
 
==Preliminary data==
 
===[[Glioblastoma]]===
 
===[[Glioblastoma]]===
#'''INCIPIENT:''' Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma. N Engl J Med. 2024 Apr 11;390(14):1290-1298. Epub 2024 Mar 13. [https://doi.org/10.1056/nejmoa2314390 link to original article] [https://pubmed.ncbi.nlm.nih.gov/38477966/ PubMed] [https://clinicaltrials.gov/study/NCT05660369 NCT05660369]
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#'''INCIPIENT:''' Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma. N Engl J Med. 2024 Apr 11;390(14):1290-1298. Epub 2024 Mar 13. [https://doi.org/10.1056/nejmoa2314390 link to original article] [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11162836/ link to PMC article] [https://pubmed.ncbi.nlm.nih.gov/38477966/ PubMed] [https://clinicaltrials.gov/study/NCT05660369 NCT05660369]
  
 
[[Category:Anti-EGFRvIII CAR T-cells]]
 
[[Category:Anti-EGFRvIII CAR T-cells]]
 
[[Category:Glioblastoma medications (investigational)]]
 
[[Category:Glioblastoma medications (investigational)]]
 
[[Category:Investigational drugs]]
 
[[Category:Investigational drugs]]

Latest revision as of 11:54, 6 July 2024

Mechanism of action

anti-EGFR variant III CAR T-cells

Preliminary data

Glioblastoma

  1. INCIPIENT: Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma. N Engl J Med. 2024 Apr 11;390(14):1290-1298. Epub 2024 Mar 13. link to original article link to PMC article PubMed NCT05660369