Prednisolone (Millipred)

General information

Class/mechanism: Corticosteroid, glucocorticoid.
Route: PO, gtt (ophthalmic eye drops)
Extravasation: n/a

• Steroid conversions

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.

Diseases for which it is used

• Acquired coagulopathy
• B-cell acute lymphoblastic leukemia
• Breast cancer
• Burkitt lymphoma
• Chronic lymphocytic leukemia
• Diffuse large B-cell lymphoma
• Extranodal NK- and T-cell lymphoma, nasal type
• Follicular lymphoma ‎
• Classical Hodgkin lymphoma
• Langerhans cell histiocytosis
• Mantle cell lymphoma
• Marginal zone lymphoma
• Multiple myeloma
• Prostate cancer

Diseases for which it was used

• Acute myeloid leukemia

Patient drug information

• Prednisolone (Millipred) patient drug information (Chemocare)
• Prednisolone (Millipred) patient drug information (UpToDate)

History of changes in EMA indication

• 1956-07-13: EURD

History of changes in PMDA indication

• 2011-09-16: New indication for the treatment of multiple myeloma.
• 2015-06-26: revised indications and a new dosage for the treatment of malignant lymphoma and similar diseases (closely-related diseases).

Also known as

• Generic names: delta(1)hydrocortisone, delta1-dehydro-hydrocortisone, deltahydrocortisone, metacortandralone, prednisolone acetate, prednisolone tebutate
• Brand names: Adnisolone, Aprednislon, Capsoid, Cortalone, Cortisolone, Cotolone, Dacortin H, Decaprednil, Decortin H, Delta-Cortef, Deltacortril, Delta-Diona, Delta-Phoricol, Deltasolone, Deltidrosol, Dhasolone, Di-Adreson-F, Dontisolon D, Estilsona, Fisopred, Frisolona, Gupisone, Hostacortin H, Hydeltra, Hydeltrasol, Klismacort, Kuhlprednon, Lenisolone, Lepi-Cortinolo, Linola-H N, Linola-H-Fett N, Longiprednil, Medicort, Meticortelone, Meti-derm, Millipred, Opredsone, Orapred, Panafcortelone, Predcor, Predicort, Precortisyl, Pred-Clysma, Predeltilone, Predni-Coelin, Prednicortelone, Predni-Helvacort, Predonine, Prelone, Prenilone, Pri-Cortin, Veripred