Difference between revisions of "Oxaliplatin (Eloxatin)"
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(Created page with "==General information== Class/mechanism: <ref name="insert">[http://products.sanofi.us/eloxatin/eloxatin.pdf Oxaliplatin (Eloxatin) package insert]</ref><ref>[http://hemonc.org/d...") |
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==General information== | ==General information== | ||
| − | Class/mechanism: <ref name="insert">[http://products.sanofi.us/eloxatin/eloxatin.pdf Oxaliplatin (Eloxatin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/oxaliplatin.pdf Oxaliplatin (Eloxatin) package insert (locally hosted backup)]</ref> | + | Class/mechanism: Platinum analog, alkylating-like, which produces interstrand and intrastrand DNA crosslinks that inhibit DNA replication and transcription, causing non-cell cycle specific cytotoxicity and death.<ref name="insert">[http://products.sanofi.us/eloxatin/eloxatin.pdf Oxaliplatin (Eloxatin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/oxaliplatin.pdf Oxaliplatin (Eloxatin) package insert (locally hosted backup)]</ref><ref>[http://www.eloxatin.com/ Eloxatin manufacturer's website]</ref> |
| − | <br>Route: | + | <br>Route: IV |
| − | <br>Extravasation: | + | <br>Extravasation: [[irritant]] (usually), [[vesicant]] (rare) |
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | ||
==Patient drug information== | ==Patient drug information== | ||
| + | *[http://products.sanofi.us/eloxatin/eloxatin.pdf#page=15 Oxaliplatin (Eloxatin) package insert PDF pages 15-16]<ref name="insert"></ref> | ||
*[http://chemocare.com/bio/oxaliplatin.asp Oxaliplatin (Eloxatin) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/oxaliplatin.asp Oxaliplatin (Eloxatin) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/bio/oxaliplatin.asp Oxaliplatin (Eloxatin) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/oxaliplatin.asp Oxaliplatin (Eloxatin) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/oxaliplatin-patient-drug-information Oxaliplatin (Eloxatin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/oxaliplatin-patient-drug-information Oxaliplatin (Eloxatin) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/oxaliplatin-patient-drug-information Oxaliplatin (Eloxatin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/oxaliplatin-patient-drug-information Oxaliplatin (Eloxatin) patient drug information (UpToDate)]</ref> | ||
Revision as of 21:16, 23 February 2012
General information
Class/mechanism: Platinum analog, alkylating-like, which produces interstrand and intrastrand DNA crosslinks that inhibit DNA replication and transcription, causing non-cell cycle specific cytotoxicity and death.[1][2][3]
Route: IV
Extravasation: irritant (usually), vesicant (rare)
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Oxaliplatin (Eloxatin) package insert PDF pages 15-16[1]
- Oxaliplatin (Eloxatin) patient drug information (Chemocare)[4]
- Oxaliplatin (Eloxatin) patient drug information (UpToDate)[5]