Difference between revisions of "Mitotane (Lysodren)"
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==General information== | ==General information== | ||
| − | Class/mechanism: Adrenal cytotoxic agent, suppresses adrenal cortex and the extra-adrenal metabolism of cortisol.<ref name="insert">[http://packageinserts.bms.com/pi/pi_lysodren.pdf Mitotane (Lysodren) package insert]</ref><ref>[ | + | Class/mechanism: Adrenal cytotoxic agent, suppresses adrenal cortex and the extra-adrenal metabolism of cortisol.<ref name="insert">[http://packageinserts.bms.com/pi/pi_lysodren.pdf Mitotane (Lysodren) package insert]</ref><ref>[[Media:Mitotane.pdf | Mitotane (Lysodren) package insert (locally hosted backup)]]</ref> |
<br>Route: PO | <br>Route: PO | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
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==Patient drug information== | ==Patient drug information== | ||
*[http://www.uptodate.com/contents/mitotane-patient-drug-information Mitotane (Lysodren) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/mitotane-patient-drug-information Mitotane (Lysodren) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/mitotane-patient-drug-information Mitotane (Lysodren) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/mitotane-patient-drug-information Mitotane (Lysodren) patient drug information (UpToDate)]</ref> | ||
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| + | ==Also known as== | ||
| + | o,p′-DDD. | ||
==References== | ==References== | ||
Revision as of 08:24, 2 March 2015
General information
Class/mechanism: Adrenal cytotoxic agent, suppresses adrenal cortex and the extra-adrenal metabolism of cortisol.[1][2]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
Also known as
o,p′-DDD.