Difference between revisions of "Binimetinib (Mektovi)"
Jump to navigation
Jump to search
Warner-admin (talk | contribs) m (Text replacement - "[[Category:Drugs FDA" to "[[Category:FDA") |
m (→Also known as) |
||
Line 11: | Line 11: | ||
=Also known as= | =Also known as= | ||
*'''Code names:''' ARRY-162, ARRY-438162, MEK162 | *'''Code names:''' ARRY-162, ARRY-438162, MEK162 | ||
− | *'''Brand name:''' Mektovi | + | *'''Brand name:''' Braftovi, Mektovi |
[[Category:Drugs]] | [[Category:Drugs]] |
Revision as of 16:16, 15 September 2019
Mechanism of action
From the NCI Drug Dictionary: An orally available inhibitor of mitogen-activated protein kinase kinase 1 and 2 (MEK1/2) with potential antineoplastic activity. Binimetinib, noncompetitive with ATP, binds to and inhibits the activity of MEK1/2.
Diseases for which it is used
History of changes in FDA indication
- 6/27/2018: Initial FDA approval in combination with Encorafenib (Braftovi) "for patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, as detected by an FDA-approved test."
Also known as
- Code names: ARRY-162, ARRY-438162, MEK162
- Brand name: Braftovi, Mektovi