Difference between revisions of "Cyclophosphamide (Cytoxan)"
| Line 8: | Line 8: | ||
==Diseases for which it is used== | ==Diseases for which it is used== | ||
*[[Acute lymphocytic leukemia]] | *[[Acute lymphocytic leukemia]] | ||
| + | *[[Aggressive Non-Hodgkin lymphoma]] | ||
| + | *[[Bladder cancer]] | ||
*[[Bone cancer]] | *[[Bone cancer]] | ||
*[[Breast cancer]] | *[[Breast cancer]] | ||
| + | *[[Central nervous system (CNS) cancer]] | ||
*[[Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL)]] | *[[Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL)]] | ||
| + | *[[Follicular lymphoma]] | ||
*[[Hodgkin lymphoma]] | *[[Hodgkin lymphoma]] | ||
| + | *[[Hodgkin lymphoma, nodular lymphocyte-predominant]] | ||
| + | *[[HIV-associated lymphoma]] | ||
| + | *[[Light-chain (AL) amyloidosis]] | ||
| + | *[[Mantle cell lymphoma]] | ||
*[[Multiple myeloma]] | *[[Multiple myeloma]] | ||
| − | *[[ | + | *[[Neuroendocrine tumors]] |
| + | *[[Prostate cancer]] | ||
| + | *[[Small cell lung cancer]] | ||
*[[Thymoma]] | *[[Thymoma]] | ||
*[[Transplant conditioning regimens]] | *[[Transplant conditioning regimens]] | ||
Revision as of 15:54, 19 June 2013
General information
Class/mechanism: Alkylating agent; transformed primarily in the liver to active metabolites which alkylate and crosslink DNA.[1][2]
Route: IV, PO
Extravasation: no information, n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape,UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Acute lymphocytic leukemia
- Aggressive Non-Hodgkin lymphoma
- Bladder cancer
- Bone cancer
- Breast cancer
- Central nervous system (CNS) cancer
- Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL)
- Follicular lymphoma
- Hodgkin lymphoma
- Hodgkin lymphoma, nodular lymphocyte-predominant
- HIV-associated lymphoma
- Light-chain (AL) amyloidosis
- Mantle cell lymphoma
- Multiple myeloma
- Neuroendocrine tumors
- Prostate cancer
- Small cell lung cancer
- Thymoma
- Transplant conditioning regimens
Patient drug information
- Cyclophosphamide (Cytoxan) patient drug information (Chemocare)[3]
- Cyclophosphamide (Cytoxan) patient drug information (UpToDate)[4]
Also known as
Alkyloxan, Biodoxan, Carloxan, Ciclofosfamida, Ciclofosfamida Filaxis, Ciclofosfamida Martian, Ciclokebir, Cyclam, Cycloblastin, Cycloblastine, Cyclo Cell, Cycloferon, Cyclomide, Cyclophar, Cyclophospham, Cyclophosphamid, cyclophosphamide monohydrate, Cyclophosphamid Farmos, Cyclophosphan, Cyclophosphan Lens, Cyclostin, Cycloxan, Cycram, Cydoxan, Cyklofosfamid, Cytophosphan, Cytoxan, Cytoxan Lyophilized, Endoxan, Endoxan-N, Endoxana, Endoxan Asta, Formitex, Genoxal, Genuxal, Hidrofosmin, Ledoxan, Ledoxina, Lyophilized Cytoxan, Neosar, Oncomide, Oncophos, Procytox, Revimmune, Sendoxan, Syklofosfamid, Trav Cyclophosphamide, Tymtran, Zycram
References
- Drug index
- Chemotherapy
- Alkylating agents
- Acute lymphocytic leukemia medications
- Bone cancer medications
- Breast cancer medications
- Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL) medications
- Hodgkin lymphoma medications
- Multiple myeloma medications
- Non-Hodgkin lymphoma medications
- Thymoma medications
- Transplant medications