Difference between revisions of "Asparaginase (Elspar)"
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==General information== | ==General information== | ||
Class/mechanism: Depletes plasma asparagine, selectively killing leukemic cells which are unable to synthesize asparagine due to a lack of asparagine synthetase.<ref name="insert">[http://www.lundbeck.com/upload/us/files/pdf/Products/Elspar_PI_US_EN.pdf Asparaginase (Elspar) package insert]</ref><ref>[[Media:Asparaginase.pdf | Asparaginase (Elspar) package insert (locally hosted backup)]]</ref> | Class/mechanism: Depletes plasma asparagine, selectively killing leukemic cells which are unable to synthesize asparagine due to a lack of asparagine synthetase.<ref name="insert">[http://www.lundbeck.com/upload/us/files/pdf/Products/Elspar_PI_US_EN.pdf Asparaginase (Elspar) package insert]</ref><ref>[[Media:Asparaginase.pdf | Asparaginase (Elspar) package insert (locally hosted backup)]]</ref> | ||
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*[http://chemocare.com/chemotherapy/drug-info/asparaginase.aspx Asparaginase (Elspar) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/asparaginase.aspx Asparaginase (Elspar) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/chemotherapy/drug-info/asparaginase.aspx Asparaginase (Elspar) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/asparaginase.aspx Asparaginase (Elspar) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/asparaginase-patient-drug-information Asparaginase (Elspar) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/asparaginase-patient-drug-information Asparaginase (Elspar) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/asparaginase-patient-drug-information Asparaginase (Elspar) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/asparaginase-patient-drug-information Asparaginase (Elspar) patient drug information (UpToDate)]</ref> | ||
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| + | ==Also known as== | ||
| + | Asparaginasa, Asparaginase Medac, Chephacardin, Colaspase, Crasnitin, Elspar, Erwina Asparaginas, Erwinase, Erwinaze, Erwinia, Erwiniase, Kidrolase, L-ASP, L-Asparaginasa Filaxis, Laspar, L Asparaginasa, L Asparaginase, L Asparaginasum, Leucoginase, Leunase, Paronal | ||
==References== | ==References== | ||
Revision as of 20:24, 3 April 2013
General information
Class/mechanism: Depletes plasma asparagine, selectively killing leukemic cells which are unable to synthesize asparagine due to a lack of asparagine synthetase.[1][2]
Route: IV, IM
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Asparaginase (Elspar) patient drug information (Chemocare)[3]
- Asparaginase (Elspar) patient drug information (UpToDate)[4]
Also known as
Asparaginasa, Asparaginase Medac, Chephacardin, Colaspase, Crasnitin, Elspar, Erwina Asparaginas, Erwinase, Erwinaze, Erwinia, Erwiniase, Kidrolase, L-ASP, L-Asparaginasa Filaxis, Laspar, L Asparaginasa, L Asparaginase, L Asparaginasum, Leucoginase, Leunase, Paronal