Difference between revisions of "Deferoxamine (Desferal)"
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Warner-admin (talk | contribs) m (Text replacement - "please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [https://online.lexi.com/lco/action/login UpToDate Lexidrug], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information" to "please refer to your preferred pharmacopeias or the prescribing information") |
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==General information== | ==General information== | ||
| − | Class/mechanism: Iron chelating agent; chelates iron from ferritin and hemosiderin but not easily from | + | Class/mechanism: Iron chelating agent; chelates iron from ferritin and hemosiderin but not easily from transferrin. Does not combine with iron from hemoglobin and cytochromes. The chelate is soluble in water and is excreted by the kidney (as well as the bile), which causes urine to appear reddish.<ref name="insert">[http://www.pharma.us.novartis.com/product/pi/pdf/desferal.pdf Deferoxamine (Desferal) package insert]</ref><ref>[[:File:Deferoxamine.pdf | Deferoxamine (Desferal) package insert (locally hosted backup)]]</ref> |
| − | transferrin. | ||
<br>Route: IM, SC, IV | <br>Route: IM, SC, IV | ||
<br>Extravasation: no information | <br>Extravasation: no information | ||
| − | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. | + | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias or the prescribing information.<ref name="insert"></ref> |
==Patient drug information== | ==Patient drug information== | ||
*[http://www.uptodate.com/contents/deferoxamine-patient-drug-information Deferoxamine (Desferal) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/deferoxamine-patient-drug-information Deferoxamine (Desferal) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/deferoxamine-patient-drug-information Deferoxamine (Desferal) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/deferoxamine-patient-drug-information Deferoxamine (Desferal) patient drug information (UpToDate)]</ref> | ||
| + | |||
| + | ==Also known as== | ||
| + | *'''Generic names:''' desferrioxamine B, desferoxamine B, DFO-B, DFOA, DFB | ||
| + | *'''Brand name:''' Desferal | ||
==References== | ==References== | ||
<references/> | <references/> | ||
| + | |||
| + | [[Category:Drugs]] | ||
| + | [[Category:Intramuscular medications]] | ||
| + | [[Category:Intravenous medications]] | ||
| + | [[Category:Subcutaneous medications]] | ||
| + | [[Category:Hematology medications]] | ||
| + | [[Category:Chelators]] | ||
| + | |||
| + | [[Category:FDA approved in 1968]] | ||
Latest revision as of 01:03, 29 June 2024
General information
Class/mechanism: Iron chelating agent; chelates iron from ferritin and hemosiderin but not easily from transferrin. Does not combine with iron from hemoglobin and cytochromes. The chelate is soluble in water and is excreted by the kidney (as well as the bile), which causes urine to appear reddish.[1][2]
Route: IM, SC, IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias or the prescribing information.[1]
Patient drug information
Also known as
- Generic names: desferrioxamine B, desferoxamine B, DFO-B, DFOA, DFB
- Brand name: Desferal