Difference between revisions of "Antithrombin III (human and recombinant)"
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==General information== | ==General information== | ||
| − | Class/mechanism: Inhibitor of thrombin, which converts fibrinogen to fibrin in the coagulation cascade and subsequent development of thrombus. | + | Class/mechanism: Inhibitor of thrombin, which converts fibrinogen to fibrin in the coagulation cascade and subsequent development of thrombus. Clinical applications include management of patients with hereditary antithrombin III (AT-III) deficiency. Please choose from the products below to find specific drug/manufacturer information: |
| − | *Antithrombin III, human (Thrombate III)<ref>[http://www.thrombate.com/ Thrombate III manufacturer's website]</ref><ref name="insert">[http://www.talecris-pi.info/inserts/thrombate.pdf Antithrombin III, human (Thrombate III) package insert]</ref><ref>[[ | + | *Antithrombin III, human (Thrombate III)<ref>[http://www.thrombate.com/ Thrombate III manufacturer's website]</ref><ref name="insert">[http://www.talecris-pi.info/inserts/thrombate.pdf Antithrombin III, human (Thrombate III) package insert]</ref><ref>[[File:Antithrombiniii.pdf | Antithrombin III, human (Thrombate III) package insert (locally hosted backup)]]</ref> |
| − | *Antithrombin III, recombinant (ATryn)<ref>[http://atryn.com/ ATryn manufacturer's website]</ref><ref name="atryn">[http://atryn.com/pdf/ATryn_PI_0409.pdf Antithrombin III, recombinant (ATryn) package insert]</ref><ref>[[ | + | *Antithrombin III, recombinant (ATryn)<ref>[http://atryn.com/ ATryn manufacturer's website]</ref><ref name="atryn">[http://atryn.com/pdf/ATryn_PI_0409.pdf Antithrombin III, recombinant (ATryn) package insert]</ref><ref>[[File:Antithrombiniiiatryn.pdf | Antithrombin III, recombinant (ATryn) package insert (locally hosted backup)]]</ref> |
Route: IV | Route: IV | ||
<br>Extravasation: no information | <br>Extravasation: no information | ||
| − | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. | + | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, UpToDate Lexidrug, [http://reference.medscape.com/drug/thrombate-iii-antithrombin-iii-342868 medscape], or the prescribing information.<ref name="insert"></ref><ref name="atryn"></ref> |
==Patient drug information== | ==Patient drug information== | ||
*[http://www.uptodate.com/contents/antithrombin-iii-patient-drug-information Antithrombin III (human and recombinant) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/antithrombin-iii-patient-drug-information Antithrombin III (human and recombinant) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/antithrombin-iii-patient-drug-information Antithrombin III (human and recombinant) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/antithrombin-iii-patient-drug-information Antithrombin III (human and recombinant) patient drug information (UpToDate)]</ref> | ||
*Brief patient counseling information can be found on [http://atryn.com/pdf/ATryn_PI_0409.pdf#page=15 page 15 of the ATryn package insert]<ref name="atryn"></ref> | *Brief patient counseling information can be found on [http://atryn.com/pdf/ATryn_PI_0409.pdf#page=15 page 15 of the ATryn package insert]<ref name="atryn"></ref> | ||
| + | |||
| + | ==Also known as== | ||
| + | *'''Brand names:''' ATryn, Thrombate III | ||
==References== | ==References== | ||
<references/> | <references/> | ||
| − | [[Category: | + | [[Category:Fractionated plasma products]] |
[[Category:Intravenous medications]] | [[Category:Intravenous medications]] | ||
| + | [[Category:Inherited coagulopathy medications]] | ||
[[Category:Hematology medications]] | [[Category:Hematology medications]] | ||
[[Category:Coagulation factors]] | [[Category:Coagulation factors]] | ||
Latest revision as of 00:15, 6 July 2024
General information
Class/mechanism: Inhibitor of thrombin, which converts fibrinogen to fibrin in the coagulation cascade and subsequent development of thrombus. Clinical applications include management of patients with hereditary antithrombin III (AT-III) deficiency. Please choose from the products below to find specific drug/manufacturer information:
Route: IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, UpToDate Lexidrug, medscape, or the prescribing information.[2][5]
Patient drug information
- Antithrombin III (human and recombinant) patient drug information (UpToDate)[7]
- Brief patient counseling information can be found on page 15 of the ATryn package insert[5]
Also known as
- Brand names: ATryn, Thrombate III
References
- ↑ Thrombate III manufacturer's website
- ↑ 2.0 2.1 Antithrombin III, human (Thrombate III) package insert
- ↑ File:Antithrombiniii.pdf
- ↑ ATryn manufacturer's website
- ↑ 5.0 5.1 5.2 Antithrombin III, recombinant (ATryn) package insert
- ↑ File:Antithrombiniiiatryn.pdf
- ↑ Antithrombin III (human and recombinant) patient drug information (UpToDate)