Difference between revisions of "Raloxifene (Evista)"
Jump to navigation
Jump to search
Warner-admin (talk | contribs) m (Text replacement - "manufacturer. Instead" to "manufacturer. Instead") |
Warner-admin (talk | contribs) m (Text replacement - "http://hemonc.org" to "https://hemonc.org") |
||
| (6 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
==General information== | ==General information== | ||
| − | Class/mechanism: SERM (selective estrogen receptor modulator), with estrogen agonist/antagonist properties depending on tissue type. Raloxifene has estrogen antagonist properties in uterine and breast tissues. However, it has estrogen agonist properties in bone, helping to decrease bone resorption.<ref name="insert">[http://pi.lilly.com/us/evista-pi.pdf Raloxifene (Evista) package insert]</ref><ref>[ | + | Class/mechanism: SERM (selective estrogen receptor modulator), with estrogen agonist/antagonist properties depending on tissue type. Raloxifene has estrogen antagonist properties in uterine and breast tissues. However, it has estrogen agonist properties in bone, helping to decrease bone resorption.<ref name="insert">[http://pi.lilly.com/us/evista-pi.pdf Raloxifene (Evista) package insert]</ref><ref>[https://hemonc.org/docs/packageinsert/raloxifene.pdf Raloxifene (Evista) package insert (locally hosted backup)]</ref> |
<br>Route: PO | <br>Route: PO | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
| Line 9: | Line 9: | ||
*[http://chemocare.com/bio/raloxifene.asp Raloxifene (Evista) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/raloxifene.asp Raloxifene (Evista) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/bio/raloxifene.asp Raloxifene (Evista) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/raloxifene.asp Raloxifene (Evista) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/raloxifene-patient-drug-information Raloxifene (Evista) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/raloxifene-patient-drug-information Raloxifene (Evista) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/raloxifene-patient-drug-information Raloxifene (Evista) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/raloxifene-patient-drug-information Raloxifene (Evista) patient drug information (UpToDate)]</ref> | ||
| + | ==History of changes in EMA indication== | ||
| + | *1998-08-05: EURD | ||
| + | ==Also known as== | ||
| + | *'''Brand names:''' Evista, Ralista, Razylan | ||
==References== | ==References== | ||
<references/> | <references/> | ||
| − | [[Category: | + | [[Category:Drugs]] |
| + | [[Category:Oral medications]] | ||
| − | |||
[[Category:Selective estrogen receptor modulators]] | [[Category:Selective estrogen receptor modulators]] | ||
| − | [[Category: | + | [[Category:FDA approved in 1997]] |
| + | [[Category:EMA approved in 1998]] | ||
Revision as of 19:30, 23 June 2024
General information
Class/mechanism: SERM (selective estrogen receptor modulator), with estrogen agonist/antagonist properties depending on tissue type. Raloxifene has estrogen antagonist properties in uterine and breast tissues. However, it has estrogen agonist properties in bone, helping to decrease bone resorption.[1][2]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Patient drug information
- Raloxifene (Evista) patient drug information (Chemocare)[3]
- Raloxifene (Evista) patient drug information (UpToDate)[4]
History of changes in EMA indication
- 1998-08-05: EURD
Also known as
- Brand names: Evista, Ralista, Razylan