Difference between revisions of "CARv3-TEAM-E T-cells"
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(Created page with "==Mechanism of action== anti-EGFR CAR T-cells ==Preliminary data== ===Glioblastoma=== #'''INCIPIENT:''' Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Ni...") |
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==Mechanism of action== | ==Mechanism of action== | ||
| − | anti-EGFR CAR T-cells | + | anti-EGFR variant III CAR T-cells |
==Preliminary data== | ==Preliminary data== | ||
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#'''INCIPIENT:''' Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma. N Engl J Med. 2024 Apr 11;390(14):1290-1298. Epub 2024 Mar 13. [https://doi.org/10.1056/nejmoa2314390 link to original article] [https://pubmed.ncbi.nlm.nih.gov/38477966/ PubMed] [https://clinicaltrials.gov/study/NCT05660369 NCT05660369] | #'''INCIPIENT:''' Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma. N Engl J Med. 2024 Apr 11;390(14):1290-1298. Epub 2024 Mar 13. [https://doi.org/10.1056/nejmoa2314390 link to original article] [https://pubmed.ncbi.nlm.nih.gov/38477966/ PubMed] [https://clinicaltrials.gov/study/NCT05660369 NCT05660369] | ||
| − | [[Category:Anti- | + | [[Category:Anti-EGFRvIII CAR T-cells]] |
[[Category:Glioblastoma medications (investigational)]] | [[Category:Glioblastoma medications (investigational)]] | ||
[[Category:Investigational drugs]] | [[Category:Investigational drugs]] | ||
Latest revision as of 18:06, 12 April 2024
Mechanism of action
anti-EGFR variant III CAR T-cells
Preliminary data
Glioblastoma
- INCIPIENT: Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma. N Engl J Med. 2024 Apr 11;390(14):1290-1298. Epub 2024 Mar 13. link to original article PubMed NCT05660369