Difference between revisions of "Vadimezan (AS-A404)"
Jump to navigation
Jump to search
(Created page with "==Mechanism of action== From the NCI Drug Dictionary: A fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines...") |
Warner-admin (talk | contribs) m (Warner-admin moved page Vadimezan (ASA404) to Vadimezan (ASA-404) without leaving a redirect) |
(No difference)
| |
Revision as of 02:07, 26 July 2023
Mechanism of action
From the NCI Drug Dictionary: A fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiogenesis. This agent also stimulates the anti-tumor activity of tumor-associated macrophages.