Difference between revisions of "Exemestane (Aromasin)"
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(Created page with "==General information== Class/mechanism: <ref name="insert">[http://labeling.pfizer.com/ShowLabeling.aspx?id=523 Exemestane (Aromasin) package insert]</ref><ref>[http://hemonc.or...") |
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==General information== | ==General information== | ||
| − | Class/mechanism: <ref name="insert">[http://labeling.pfizer.com/ShowLabeling.aspx?id=523 Exemestane (Aromasin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/exemestane.pdf Exemestane (Aromasin) package insert (locally hosted backup)]</ref> | + | Class/mechanism: Steroidal aromatase inhibitor; irreversibly binds and inactivates the aromatase enzyme that converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.<ref name="insert">[http://labeling.pfizer.com/ShowLabeling.aspx?id=523 Exemestane (Aromasin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/exemestane.pdf Exemestane (Aromasin) package insert (locally hosted backup)]</ref> |
| − | <br>Route: | + | <br>Route: PO |
| − | <br>Extravasation: | + | <br>Extravasation: n/a |
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | ||
Revision as of 04:06, 14 January 2012
General information
Class/mechanism: Steroidal aromatase inhibitor; irreversibly binds and inactivates the aromatase enzyme that converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.[1][2]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Exemestane (Aromasin) patient drug information (Chemocare)[3]
- Exemestane (Aromasin) patient drug information (UpToDate)[4]