Difference between revisions of "Renal cell carcinoma, VHL-associated"

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|[https://www.ncbi.nlm.nih.gov/pmc/articles/pmc9275515/ Jonasch et al. 2021 (MK-6482-004)]
 
|[https://www.ncbi.nlm.nih.gov/pmc/articles/pmc9275515/ Jonasch et al. 2021 (MK-6482-004)]
|2018-2019
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{| class="wikitable" style="margin:auto; color:white; background-color:#1B4F26"
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|'''[https://www.esmo.org/guidelines/esmo-mcbs/esmo-mcbs-scorecards/scorecard-314-1 <span style="color:white;">ESMO-MCBS (3)</span>]'''
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|5/31/2018-3/29/2019
 
| style="background-color:#91cf61" |Phase 2 (RT)
 
| style="background-color:#91cf61" |Phase 2 (RT)
 
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Revision as of 13:48, 5 March 2023

Section editor transclusions Note: these are regimens tested in populations with a diagnosis of Von Hippel Lindau (VHL) Disease-associated renal cell carcinoma, please see the main RCC page for other regimens.

1 regimens on this page
1 variants on this page


All lines of therapy

Belzutifan monotherapy

Regimen

Study Years of enrollment Evidence
Jonasch et al. 2021 (MK-6482-004)
ESMO-MCBS (3)
5/31/2018-3/29/2019 Phase 2 (RT)

Targeted therapy

Continued indefinitely

References

  1. MK-6482-004: Jonasch E, Donskov F, Iliopoulos O, Rathmell WK, Narayan VK, Maughan BL, Oudard S, Else T, Maranchie JK, Welsh SJ, Thamake S, Park EK, Perini RF, Linehan WM, Srinivasan R; MK-6482-004 Investigators. Belzutifan for Renal Cell Carcinoma in von Hippel-Lindau Disease. N Engl J Med. 2021 Nov 25;385(22):2036-2046. link to original article contains dosing details in manuscript link to PMC article Pubmed NCT03401788