Difference between revisions of "Plerixafor (Mozobil)"
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*[http://www.uptodate.com/contents/plerixafor-patient-drug-information Plerixafor (Mozobil) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/plerixafor-patient-drug-information Plerixafor (Mozobil) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/plerixafor-patient-drug-information Plerixafor (Mozobil) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/plerixafor-patient-drug-information Plerixafor (Mozobil) patient drug information (UpToDate)]</ref> | ||
| + | ==History of changes in EMA indication== | ||
| + | *7/30/2009: Initial authorization | ||
==Also known as== | ==Also known as== | ||
*'''Code name:''' AMD3100 | *'''Code name:''' AMD3100 | ||
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[[Category:FDA approved in 2008]] | [[Category:FDA approved in 2008]] | ||
| + | [[Category:EMA approved in 2009]] | ||
[[Category:PMDA approved drugs]] | [[Category:PMDA approved drugs]] | ||
Revision as of 14:42, 2 January 2023
General information
Class/mechanism: Mobilizes hematopoetic stem cells by inhibiting the CXCR4 chemokine receptor and blocking its cognate ligand, stromal cell-derived factor-1α (SDF-1α). One function of CXCR4 is to anchor stem cells to the marrow matrix via SDF-1α or other adhesion molecules.[1][2]
Route: SC
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
History of changes in EMA indication
- 7/30/2009: Initial authorization
Also known as
- Code name: AMD3100
- Brand name: Mozobil