Difference between revisions of "Goserelin (Zoladex)"
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==General information== | ==General information== | ||
| − | Class/mechanism: Gonadotropin-releasing hormone (GnRH) analog, inhibits pituitary gonadotropin secretion, which suppresses ovarian and testicular steroidogenesis<ref name="insert">[http://documents.tersera.com/zoladex-us/10.8mg_MagnumPI.pdf Goserelin (Zoladex) package insert]</ref><ref>[[File:Goserelin.pdf | Goserelin (Zoladex) package insert (locally hosted backup)]]</ref> | + | Class/mechanism: Gonadotropin-releasing hormone (GnRH) analog, inhibits pituitary gonadotropin secretion, which suppresses ovarian and testicular steroidogenesis<ref name="insert">[http://documents.tersera.com/zoladex-us/10.8mg_MagnumPI.pdf Goserelin (Zoladex) package insert]</ref><ref>[[:File:Goserelin.pdf | Goserelin (Zoladex) package insert (locally hosted backup)]]</ref> |
<br>Route: SC | <br>Route: SC | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
Revision as of 03:56, 20 September 2021
General information
Class/mechanism: Gonadotropin-releasing hormone (GnRH) analog, inhibits pituitary gonadotropin secretion, which suppresses ovarian and testicular steroidogenesis[1][2]
Route: SC
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Patient counseling information can be found in the package insert[1]
- Goserelin (Zoladex) patient drug information (Chemocare)[3]
- Goserelin (Zoladex) patient drug information (UpToDate)[4]
History of changes in FDA indication
- 12/29/1989: Initial FDA approval for palliative treatment of advanced carcinoma of the prostate
Also known as
- Generic name: goserelin acetate
- Brand names: Novgos, Zoladex