Difference between revisions of "Argatroban (Acova)"
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==General information== | ==General information== | ||
| − | Class/mechanism: Direct thrombin inhibitor, binds reversibly to free and clot-associated thrombin and inhibits its effects of catalyzing the formation of fibrin from fibrinogen, platelet aggregation, activation of protein C, and activation of coagulation factors V, VIII, and XIII.<ref name="insert">[https://www.gsksource.com/ | + | Class/mechanism: Direct thrombin inhibitor, binds reversibly to free and clot-associated thrombin and inhibits its effects of catalyzing the formation of fibrin from fibrinogen, platelet aggregation, activation of protein C, and activation of coagulation factors V, VIII, and XIII.<ref name="insert">[https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Argatroban/pdf/ARGATROBAN.PDF Argatroban package insert]</ref><ref>[[:File:Argatroban.pdf | Argatroban package insert (locally hosted backup)]]</ref><ref>[https://www.gsksource.com/argatroban Argatroban manufacturer's website]</ref> |
<br>Route: IV | <br>Route: IV | ||
<br>Extravasation: no information | <br>Extravasation: no information | ||
| − | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. | + | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://reference.medscape.com/drug/acova-argatroban-342145 Medscape], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> |
==Patient drug information== | ==Patient drug information== | ||
| + | *Brief patient counseling information can be found in the [https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Argatroban/pdf/ARGATROBAN.PDF Argatroban package insert]<ref name="insert"></ref> | ||
*[http://www.uptodate.com/contents/argatroban-patient-drug-information Argatroban patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/argatroban-patient-drug-information Argatroban patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/argatroban-patient-drug-information Argatroban patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/argatroban-patient-drug-information Argatroban patient drug information (UpToDate)]</ref> | ||
| + | |||
| + | ==Also known as== | ||
| + | *'''Brand names:''' Acova, Exembol, Novastan | ||
==References== | ==References== | ||
<references/> | <references/> | ||
| + | |||
| + | [[Category:Drugs]] | ||
| + | [[Category:Intravenous medications]] | ||
| + | [[Category:Anticoagulants]] | ||
| + | [[Category:Direct thrombin inhibitors]] | ||
| + | |||
| + | [[Category:Heparin-induced thrombocytopenia medications]] | ||
| + | [[Category:Venous thromboembolism medications]] | ||
| + | |||
| + | [[Category:FDA approved in 2000]] | ||
Revision as of 03:39, 20 September 2021
General information
Class/mechanism: Direct thrombin inhibitor, binds reversibly to free and clot-associated thrombin and inhibits its effects of catalyzing the formation of fibrin from fibrinogen, platelet aggregation, activation of protein C, and activation of coagulation factors V, VIII, and XIII.[1][2][3]
Route: IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Patient drug information
- Brief patient counseling information can be found in the Argatroban package insert[1]
- Argatroban patient drug information (UpToDate)[4]
Also known as
- Brand names: Acova, Exembol, Novastan