Difference between revisions of "Goserelin (Zoladex)"

From HemOnc.org - A Hematology Oncology Wiki
Jump to navigation Jump to search
Line 16: Line 16:
  
 
==History of changes in FDA indication==
 
==History of changes in FDA indication==
* 12/29/1989: Initial FDA approval (label not available on Drugs @ FDA)
+
* 12/29/1989: Initial FDA approval for palliative treatment of advanced [[prostate cancer|carcinoma of the prostate]]
  
 
==Also known as==
 
==Also known as==

Revision as of 01:42, 23 September 2020

General information

Class/mechanism: Gonadotropin-releasing hormone (GnRH) analog, inhibits pituitary gonadotropin secretion, which suppresses ovarian and testicular steroidogenesis[1][2]
Route: SC
Extravasation: n/a

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Diseases for which it is used

Patient drug information

History of changes in FDA indication

Also known as

  • Generic name: goserelin acetate
  • Brand names: Novgos, Zoladex

References