Difference between revisions of "Tafasitamab (Monjuvi)"

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m (Jwarner moved page MOR208 to Tafasitamab (Monjuvi): FDA approval)
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Revision as of 22:23, 3 August 2020

Mechanism of action

Anti-CD19 antibody with an engineered Fc region to enhance Fcγ receptor binding affinity

Diseases for which it is used

  1. Abstract: Kami J. Maddocks, Eva González Barca, Wojciech Jurczak, Anna Marina Liberati, Johannes Duell, Zsolt Nagy, Tomáš Papajík, Marc Andre, Nagesh Kalakonda, Martin H. Dreyling, Pier Luigi Zinzani, Sumeet Vijay Ambarkhane, Johannes Weirather, and Gilles A. Salles. L-mind: MOR208 combined with lenalidomide (LEN) in patients with relapsed or refractory diffuse large b-cell lymphoma (R-R DLBCL)—A single-arm phase II study. Journal of Clinical Oncology 2017 35:15_suppl, 7514-7514 link to abstract

History of changes in FDA indication

Also known as

  • Code names: MOR208, MOR00208, XmAb5574
  • Generic name: tafasitamab-cxix
  • Brand name: Monjuvi