Difference between revisions of "HemOnc vocabulary concepts"
m |
m |
||
| Line 3: | Line 3: | ||
=Condition-level concepts= | =Condition-level concepts= | ||
==Condition== | ==Condition== | ||
| − | Examples: acquired coagulopathy, acute myeloid leukemia, adrenocortical carcinoma | + | In the HemOnc vocabulary, a condition is the granular level at which treatments have been evaluated. For example, [[Colon cancer]] and [[Rectal cancer]] are conditions, whereas [[:Category:Colorectal cancers|Colorectal cancer]] is a [[#Condition Class|Condition Class]]. |
| + | *Examples: acquired coagulopathy, acute myeloid leukemia, adrenocortical carcinoma | ||
==Condition Class== | ==Condition Class== | ||
Examples: classical hematologic condition, leukemia, malignant solid neoplasm | Examples: classical hematologic condition, leukemia, malignant solid neoplasm | ||
| Line 23: | Line 24: | ||
=Component-level concepts= | =Component-level concepts= | ||
==Brand Name== | ==Brand Name== | ||
| − | Examples: Abatoarin, Acetisal, Aclacin | + | These are US and non-US brand names for drugs. |
| + | *Examples: Abatoarin, Acetisal, Aclacin | ||
==Component== | ==Component== | ||
Examples: abciximab, abemaciclib, abexinostat | Examples: abciximab, abemaciclib, abexinostat | ||
| Line 57: | Line 59: | ||
Examples: Blood Adv, N Engl J Med, Ann Oncol | Examples: Blood Adv, N Engl J Med, Ann Oncol | ||
==PubMedURL== | ==PubMedURL== | ||
| − | Example: https://www.ncbi.nlm.nih.gov/pubmed/10202164 | + | Most of the references included in the HemOnc vocabulary are also indexed in MEDLINE. When this is the case, we also include a direct hyperlink to the PubMed abstract. |
| + | *Example: https://www.ncbi.nlm.nih.gov/pubmed/10202164 | ||
==Reference== | ==Reference== | ||
Examples: ABSOLUTE::00, Abrey et al. 2000::01 | Examples: ABSOLUTE::00, Abrey et al. 2000::01 | ||
| Line 63: | Line 66: | ||
Example: A comparative study of two regimens of combination chemotherapy in acute leukemia | Example: A comparative study of two regimens of combination chemotherapy in acute leukemia | ||
==ReferenceURL== | ==ReferenceURL== | ||
| − | Example: http://ar.iiarjournals.org/content/31/6/2297.long | + | This is the direct hyperlink to the publication described by the '''[[#Reference|Reference]]''' concept. |
| + | *Example: http://ar.iiarjournals.org/content/31/6/2297.long | ||
=Author-level concepts= | =Author-level concepts= | ||
==Author== | ==Author== | ||
Revision as of 20:57, 27 January 2020
This page has short descriptions and examples of the concepts that have been parsed into the HemOnc ontology. Note that this is NOT the full HemOnc chemotherapy regimen model, as there are still concepts that are in the process of being defined and parsed. For information about how to obtain a copy of the ontology please go to this page.
Condition-level concepts
Condition
In the HemOnc vocabulary, a condition is the granular level at which treatments have been evaluated. For example, Colon cancer and Rectal cancer are conditions, whereas Colorectal cancer is a Condition Class.
- Examples: acquired coagulopathy, acute myeloid leukemia, adrenocortical carcinoma
Condition Class
Examples: classical hematologic condition, leukemia, malignant solid neoplasm
Context
Examples: adjuvant therapy, non-curative first-line induction therapy, upfront therapy
Regimen-level concepts
Cycle Sigs
Examples: 14-day cycle for up to 8 cycles, 21-day cycle for 4 cycles, 21-day cycle for up to 35 cycles (2 years)
Modality
Examples: anticoagulation, chemotherapy, immunotherapy
Regimen
Examples: 7 plus 3d, 7 plus 3d and Midostaurin, R-CHOP
Regimen Class
Examples: platinum doublet, bevacizumab-containing regimen
Regimen Stub
Examples: FULV and Trimetrexate, Plitidespin and Dexamethasone
Component-level concepts
Brand Name
These are US and non-US brand names for drugs.
- Examples: Abatoarin, Acetisal, Aclacin
Component
Examples: abciximab, abemaciclib, abexinostat
Component Class
Examples: 5 alpha-reductase inhibitor, AKT1 inhibitor, anthracycline
Procedure
Examples: adrenalectomy, lymphadenectomy, interval debulking surgery
Rad Sig
Example: 1.1 Gy fractions x 70 fractions, given twice per day, 5 times per week (total dose: 77 Gy)
Route
Examples: intravenous, oral, subcutaneous
Sig
Example: 0.4 mg/m^2/day IV continuous infusion over 96 hours, started on day 1 (total dose per cycle: 1.6 mg/m^2)
Sig Stub
Example: (dose not specified) IT once per day on days 22 and 43
Study-level concepts
Endpoint
Examples: CR rate after first induction, DFS36, OS
Experimental design
Examples: de-escalation, escalation, in-class switch, out-of-class switch
Study
Examples: ABSOLUTE, ACOSOG Z1031, ECOG E3483
Study Class
Example: FDA registration study
Study Group
Examples: Eastern Cooperative Oncology Group, EINSTEIN Investigators, EORTC Children Leukemia Group
Study name short
Examples: Adelstein et al. 2003, Adelstein et al. 2010, Alberts et al. 1989
Publication-level concepts
Journal
Examples: Blood Adv, N Engl J Med, Ann Oncol
PubMedURL
Most of the references included in the HemOnc vocabulary are also indexed in MEDLINE. When this is the case, we also include a direct hyperlink to the PubMed abstract.
Reference
Examples: ABSOLUTE::00, Abrey et al. 2000::01
ReferenceTitle
Example: A comparative study of two regimens of combination chemotherapy in acute leukemia
ReferenceURL
This is the direct hyperlink to the publication described by the Reference concept.
Author-level concepts
Author
Author names, in the format of Last-Name_First/Middle.
- Examples: Abbruzzese_Alberto, Abbruzzese_James L, Abernethy_Amy
Generic concepts
Year
Examples: 1946, 2020