Difference between revisions of "HemOnc vocabulary concepts"

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==Context==
 
==Context==
 
Examples: adjuvant therapy, non-curative first-line induction therapy, upfront therapy
 
Examples: adjuvant therapy, non-curative first-line induction therapy, upfront therapy
==Procedure==
 
Examples: adrenalectomy, lymphadenectomy, interval debulking surgery
 
  
 
=Regimen-level concepts=
 
=Regimen-level concepts=
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==Component Class==
 
==Component Class==
 
Examples: 5 alpha-reductase inhibitor, AKT1 inhibitor, anthracycline
 
Examples: 5 alpha-reductase inhibitor, AKT1 inhibitor, anthracycline
 +
==Procedure==
 +
Examples: adrenalectomy, lymphadenectomy, interval debulking surgery
 
==Rad Sig==
 
==Rad Sig==
 
Example: 1.1 Gy fractions x 70 fractions, given twice per day, 5 times per week (total dose: 77 Gy)
 
Example: 1.1 Gy fractions x 70 fractions, given twice per day, 5 times per week (total dose: 77 Gy)
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==Study==
 
==Study==
 
Examples: ABSOLUTE, ACOSOG Z1031, ECOG E3483
 
Examples: ABSOLUTE, ACOSOG Z1031, ECOG E3483
 +
==Study Class==
 +
Example: FDA registration study
 
==Study Group==
 
==Study Group==
 
Examples: Eastern Cooperative Oncology Group, EINSTEIN Investigators, EORTC Children Leukemia Group
 
Examples: Eastern Cooperative Oncology Group, EINSTEIN Investigators, EORTC Children Leukemia Group
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=Publication-level concepts=
 
=Publication-level concepts=
 
==Journal==
 
==Journal==
 +
Examples: Blood Adv, N Engl J Med, Ann Oncol
 
==PubMedURL==
 
==PubMedURL==
 +
Example: https://www.ncbi.nlm.nih.gov/pubmed/10202164
 
==Reference==
 
==Reference==
 +
Examples: ABSOLUTE::00, Abrey et al. 2000::01
 
==ReferenceTitle==
 
==ReferenceTitle==
 +
Example: A comparative study of two regimens of combination chemotherapy in acute leukemia
 
==ReferenceURL==
 
==ReferenceURL==
 
+
Example: http://ar.iiarjournals.org/content/31/6/2297.long
 
=Author-level concepts=
 
=Author-level concepts=
 
==Author==
 
==Author==
 
+
Author names, in the format of Last-Name_First/Middle.
 +
*Examples: Abbruzzese_Alberto, Abbruzzese_James L, Abernethy_Amy
 
=Generic concepts=
 
=Generic concepts=
 
==Year==
 
==Year==
 +
Examples: 1946, 2020
  
 
[[Category:Ontology pages]]
 
[[Category:Ontology pages]]

Revision as of 20:48, 27 January 2020

This page has short descriptions and examples of the concepts that have been parsed into the HemOnc ontology. Note that this is NOT the full HemOnc chemotherapy regimen model, as there are still concepts that are in the process of being defined and parsed. For information about how to obtain a copy of the ontology please go to this page.

Condition-level concepts

Condition

Examples: acquired coagulopathy, acute myeloid leukemia, adrenocortical carcinoma

Condition Class

Examples: classical hematologic condition, leukemia, malignant solid neoplasm

Context

Examples: adjuvant therapy, non-curative first-line induction therapy, upfront therapy

Regimen-level concepts

Cycle Sigs

Examples: 14-day cycle for up to 8 cycles, 21-day cycle for 4 cycles, 21-day cycle for up to 35 cycles (2 years)

Modality

Examples: anticoagulation, chemotherapy, immunotherapy

Regimen

Examples: 7 plus 3d, 7 plus 3d and Midostaurin, R-CHOP

Regimen Class

Examples: platinum doublet, bevacizumab-containing regimen

Regimen Stub

Examples: FULV and Trimetrexate, Plitidespin and Dexamethasone

Component-level concepts

Brand Name

Examples: Abatoarin, Acetisal, Aclacin

Component

Examples: abciximab, abemaciclib, abexinostat

Component Class

Examples: 5 alpha-reductase inhibitor, AKT1 inhibitor, anthracycline

Procedure

Examples: adrenalectomy, lymphadenectomy, interval debulking surgery

Rad Sig

Example: 1.1 Gy fractions x 70 fractions, given twice per day, 5 times per week (total dose: 77 Gy)

Route

Examples: intravenous, oral, subcutaneous

Sig

Example: 0.4 mg/m^2/day IV continuous infusion over 96 hours, started on day 1 (total dose per cycle: 1.6 mg/m^2)

Sig Stub

Example: (dose not specified) IT once per day on days 22 and 43

Study-level concepts

Endpoint

Examples: CR rate after first induction, DFS36, OS

Experimental design

Examples: de-escalation, escalation, in-class switch, out-of-class switch

Study

Examples: ABSOLUTE, ACOSOG Z1031, ECOG E3483

Study Class

Example: FDA registration study

Study Group

Examples: Eastern Cooperative Oncology Group, EINSTEIN Investigators, EORTC Children Leukemia Group

Study name short

Examples: Adelstein et al. 2003, Adelstein et al. 2010, Alberts et al. 1989

Publication-level concepts

Journal

Examples: Blood Adv, N Engl J Med, Ann Oncol

PubMedURL

Example: https://www.ncbi.nlm.nih.gov/pubmed/10202164

Reference

Examples: ABSOLUTE::00, Abrey et al. 2000::01

ReferenceTitle

Example: A comparative study of two regimens of combination chemotherapy in acute leukemia

ReferenceURL

Example: http://ar.iiarjournals.org/content/31/6/2297.long

Author-level concepts

Author

Author names, in the format of Last-Name_First/Middle.

  • Examples: Abbruzzese_Alberto, Abbruzzese_James L, Abernethy_Amy

Generic concepts

Year

Examples: 1946, 2020