Revision as of 23:48, 11 January 2020

1 regimens on this page 1 variants on this page

All lines of therapy

Study	Evidence
Hainsworth et al. 2018 (MyPathway)	Phase IIa, <20 pts in this arm

Gene: EGFR
Alteration: nonsynonymous exon 18 or exon 21 mutations, or exon 19 deletions
Acceptable methods of measurement: molecular profiling performed on tissue obtained at the most recent tumor biopsy
Biomarker exclusions: EGFR exon 20 mutations

Continued indefinitely

MyPathway: Hainsworth JD, Meric-Bernstam F, Swanton C, Hurwitz H, Spigel DR, Sweeney C, Burris H, Bose R, Yoo B, Stein A, Beattie M, Kurzrock R. Targeted therapy for advanced solid tumors on the basis of molecular profiles: results from MyPathway, an open-label, phase IIa multiple basket study. J Clin Oncol. 2018 Feb 20;36(6):536-542. Epub 2018 Jan 10. link to original article contains verified protocol PubMed

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 =All lines of therapy=
 ==Erlotinib monotherapy {{#subobject:e0d17a|Regimen=1}}==
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 [[Category:EGFR regimens]]
 [[Category:Biomarker-specific pages]]
+[[Category:Malignant solid neoplasm]]
 [[Category:Site-agnostic regimens]]