Difference between revisions of "Arsenic trioxide (Trisenox)"
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==General information== | ==General information== | ||
− | Class/mechanism: Causes damage or degradation of PML-RAR alpha fusion protein, causes apoptosis-type changes in NB4 human promyelocytic leukemia cells in vitro.<ref name="insert">[http://www.drugbank.ca/system/fda_labels/DB01169.pdf?1265922813 Arsenic trioxide (Trisenox) package insert]</ref><ref>[http://hemonc.org/docs/ | + | Class/mechanism: Causes damage or degradation of PML-RAR alpha fusion protein, causes apoptosis-type changes in NB4 human promyelocytic leukemia cells in vitro.<ref name="insert">[http://www.drugbank.ca/system/fda_labels/DB01169.pdf?1265922813 Arsenic trioxide (Trisenox) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/arsenictrioxide.pdf Arsenic trioxide (Trisenox) package insert (locally hosted backup)]</ref> |
<br>Route: IV | <br>Route: IV | ||
<br>Extravasation: [[irritant]] | <br>Extravasation: [[irritant]] |
Revision as of 16:29, 29 November 2011
General information
Class/mechanism: Causes damage or degradation of PML-RAR alpha fusion protein, causes apoptosis-type changes in NB4 human promyelocytic leukemia cells in vitro.[1][2]
Route: IV
Extravasation: irritant
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