Difference between revisions of "Deferoxamine (Desferal)"
Warner-admin (talk | contribs) m (Text replacement - "Category:Drug index" to "Category:Drugs") |
m |
||
| Line 1: | Line 1: | ||
| − | |||
| − | |||
==General information== | ==General information== | ||
Class/mechanism: Iron chelating agent; chelates iron from ferritin and hemosiderin but not easily from transferrin. Does not combine with iron from hemoglobin and cytochromes. The chelate is soluble in water and is excreted by the kidney (as well as the bile), which causes urine to appear reddish.<ref name="insert">[http://www.pharma.us.novartis.com/product/pi/pdf/desferal.pdf Deferoxamine (Desferal) package insert]</ref><ref>[[Media:Deferoxamine.pdf | Deferoxamine (Desferal) package insert (locally hosted backup)]]</ref> | Class/mechanism: Iron chelating agent; chelates iron from ferritin and hemosiderin but not easily from transferrin. Does not combine with iron from hemoglobin and cytochromes. The chelate is soluble in water and is excreted by the kidney (as well as the bile), which causes urine to appear reddish.<ref name="insert">[http://www.pharma.us.novartis.com/product/pi/pdf/desferal.pdf Deferoxamine (Desferal) package insert]</ref><ref>[[Media:Deferoxamine.pdf | Deferoxamine (Desferal) package insert (locally hosted backup)]]</ref> | ||
| Line 10: | Line 8: | ||
==Patient drug information== | ==Patient drug information== | ||
*[http://www.uptodate.com/contents/deferoxamine-patient-drug-information Deferoxamine (Desferal) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/deferoxamine-patient-drug-information Deferoxamine (Desferal) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/deferoxamine-patient-drug-information Deferoxamine (Desferal) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/deferoxamine-patient-drug-information Deferoxamine (Desferal) patient drug information (UpToDate)]</ref> | ||
| + | |||
| + | ==Also known as== | ||
| + | *'''Generic names:''' desferrioxamine B, desferoxamine B, DFO-B, DFOA, DFB | ||
| + | *'''Brand name:''' Desferal | ||
==References== | ==References== | ||
| Line 15: | Line 17: | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
| + | [[Category:Intramuscular medications]] | ||
| + | [[Category:Intravenous medications]] | ||
| + | [[Category:Subcutaneous medications]] | ||
[[Category:Hematology medications]] | [[Category:Hematology medications]] | ||
[[Category:Chelators]] | [[Category:Chelators]] | ||
[[Category:Drugs FDA approved in 1968]] | [[Category:Drugs FDA approved in 1968]] | ||
Revision as of 18:56, 23 July 2018
General information
Class/mechanism: Iron chelating agent; chelates iron from ferritin and hemosiderin but not easily from transferrin. Does not combine with iron from hemoglobin and cytochromes. The chelate is soluble in water and is excreted by the kidney (as well as the bile), which causes urine to appear reddish.[1][2]
Route: IM, SC, IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Patient drug information
Also known as
- Generic names: desferrioxamine B, desferoxamine B, DFO-B, DFOA, DFB
- Brand name: Desferal