Difference between revisions of "Caplacizumab (Cablivi)"

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m (Jwarner moved page Caplacizumab to Caplacizumab (ALX-0081))
m (Text replacement - "Category:Drug index" to "Category:Drugs")
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# Peyvandi F, Scully M, Kremer Hovinga JA, Cataland S, Knöbl P, Wu H, Artoni A, Westwood JP, Mansouri Taleghani M, Jilma B, Callewaert F, Ulrichts H, Duby C, Tersago D; TITAN Investigators. Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura. N Engl J Med. 2016 Feb 11;374(6):511-522. [http://www.nejm.org/doi/full/10.1056/NEJMoa1505533 link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/26863353 PubMed]
 
# Peyvandi F, Scully M, Kremer Hovinga JA, Cataland S, Knöbl P, Wu H, Artoni A, Westwood JP, Mansouri Taleghani M, Jilma B, Callewaert F, Ulrichts H, Duby C, Tersago D; TITAN Investigators. Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura. N Engl J Med. 2016 Feb 11;374(6):511-522. [http://www.nejm.org/doi/full/10.1056/NEJMoa1505533 link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/26863353 PubMed]
  
[[Category:Drug index]]
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[[Category:Drugs]]
 
[[Category:Antibody medications]]
 
[[Category:Antibody medications]]
 
[[Category:Anti-vWF medications]]
 
[[Category:Anti-vWF medications]]

Revision as of 22:52, 13 June 2018

Mechanism of action

A single domain antibody directed against the A1 domain of von Willebrand factor (vWF).

Preliminary data

Thrombotic thrombocytopenic purpura

  1. Peyvandi F, Scully M, Kremer Hovinga JA, Cataland S, Knöbl P, Wu H, Artoni A, Westwood JP, Mansouri Taleghani M, Jilma B, Callewaert F, Ulrichts H, Duby C, Tersago D; TITAN Investigators. Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura. N Engl J Med. 2016 Feb 11;374(6):511-522. link to original article PubMed