Difference between revisions of "Lomustine (CCNU)"
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==Diseases for which it is used== | ==Diseases for which it is used== | ||
*[[Acute myeloid leukemia]] | *[[Acute myeloid leukemia]] | ||
| − | *[[ | + | *[[Anaplastic glioma]] |
*[[CNS lymphoma]] | *[[CNS lymphoma]] | ||
| + | *[[Colon cancer]] | ||
| + | *[[Glioblastoma]] | ||
| + | *[[Low-grade glioma]] | ||
| + | |||
| + | ==Diseases for which it was used== | ||
| + | *[[Hodgkin lymphoma - obsolete|Hodgkin lymphoma]] | ||
| + | *[[Non-small cell lung cancer - obsolete|Non-small cell lung cancer]] | ||
==Patient drug information== | ==Patient drug information== | ||
| Line 24: | Line 31: | ||
[[Category:Drug index]] | [[Category:Drug index]] | ||
| − | |||
[[Category:Oral medications]] | [[Category:Oral medications]] | ||
| Line 30: | Line 36: | ||
[[Category:Acute myeloid leukemia medications]] | [[Category:Acute myeloid leukemia medications]] | ||
| − | [[Category: | + | [[Category:Anaplastic glioma medications]] |
[[Category:Central nervous system (CNS) lymphoma medications]] | [[Category:Central nervous system (CNS) lymphoma medications]] | ||
| + | [[Category:Colon cancer medications]] | ||
| + | [[Category:Glioblastoma medications]] | ||
| + | [[Category:Low-grade glioma medications]] | ||
[[Category:Drugs FDA approved in 1976]] | [[Category:Drugs FDA approved in 1976]] | ||
Revision as of 15:59, 20 January 2018
General information
Class/mechanism: Nitrosourea, alkylates DNA and RNA and may inhibit certain key enzymatic reactions by carbamoylation of amino acids in proteins.[1][2]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Diseases for which it was used
Patient drug information
- Lomustine (Ceenu) patient drug information (Chemocare)[3]
- Lomustine (Ceenu) patient drug information (UpToDate)[4]
Also known as
- Generic names: CCNU, MeCCNU
- Brand names: CeeNu, Gleostine
References
- ↑ 1.0 1.1 Lomustine (Ceenu) package insert
- ↑ Lomustine (Ceenu) package insert (locally hosted backup)
- ↑ Lomustine (Ceenu) patient drug information (Chemocare)
- ↑ Lomustine (Ceenu) patient drug information (UpToDate)
- ↑ Discontinued drug bulletin: Lomustine capsules (American Society of Health-System Pharmacists)
- ↑ NextSource Biotechnology Lomustine (CCNU) update