Difference between revisions of "Exemestane (Aromasin)"
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==General information== | ==General information== | ||
| − | Class/mechanism: Steroidal aromatase inhibitor; irreversibly binds and inactivates the aromatase enzyme that converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.<ref name="insert">[http://labeling.pfizer.com/ShowLabeling.aspx?id=523 Exemestane (Aromasin) package insert]</ref><ref>[ | + | Class/mechanism: Steroidal aromatase inhibitor; irreversibly binds and inactivates the aromatase enzyme that converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.<ref name="insert">[http://labeling.pfizer.com/ShowLabeling.aspx?id=523 Exemestane (Aromasin) package insert]</ref><ref>[[Media:Exemestane.pdf | Exemestane (Aromasin) package insert (locally hosted backup)]]</ref><ref>[http://aromasin.com Aromasin manufacturer's website]</ref> |
<br>Route: PO | <br>Route: PO | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | ||
| + | |||
| + | ==Diseases for which it is used== | ||
| + | *[[Breast cancer]] | ||
==Patient drug information== | ==Patient drug information== | ||
| − | *[http://chemocare.com/ | + | *[http://labeling.pfizer.com/ShowLabeling.aspx?id=523#page=16 Exemestane (Aromasin) package insert pages 16-17]<ref name="insert"></ref> |
| + | *Brief patient counseling information can be found on [http://labeling.pfizer.com/ShowLabeling.aspx?id=523#page=15 page 15 of the Exemestane (Aromasin) package insert]<ref name="insert"></ref> | ||
| + | *[http://chemocare.com/chemotherapy/drug-info/exemestane.aspx Exemestane (Aromasin) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/exemestane.aspx Exemestane (Aromasin) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/exemestane-patient-drug-information Exemestane (Aromasin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/exemestane-patient-drug-information Exemestane (Aromasin) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/exemestane-patient-drug-information Exemestane (Aromasin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/exemestane-patient-drug-information Exemestane (Aromasin) patient drug information (UpToDate)]</ref> | ||
==References== | ==References== | ||
<references/> | <references/> | ||
| + | |||
| + | [[Category:Drug index]] | ||
| + | [[Category:Steroid synthesis inhibitors]] | ||
| + | [[Category:Aromatase inhibitors]] | ||
| + | [[Category:Breast cancer medications]] | ||
Revision as of 19:44, 4 November 2012
General information
Class/mechanism: Steroidal aromatase inhibitor; irreversibly binds and inactivates the aromatase enzyme that converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.[1][2][3]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Exemestane (Aromasin) package insert pages 16-17[1]
- Brief patient counseling information can be found on page 15 of the Exemestane (Aromasin) package insert[1]
- Exemestane (Aromasin) patient drug information (Chemocare)[4]
- Exemestane (Aromasin) patient drug information (UpToDate)[5]