Difference between revisions of "Levels of Evidence"

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(Created page with "The purpose of this page is to create a reference to describe our methodology for assigning levels of evidence to regimens. We have taken a simplified approach to rating evid...")
 
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The purpose of this page is to create a reference to describe our methodology for assigning levels of evidence to regimens.  We have taken a simplified approach to rating evidence, based on a three-color metric (red/yellow/green).  Of course, there are finer gradations of the quality of evidence so this simplified scheme should be taken with a grain of salt.
 
The purpose of this page is to create a reference to describe our methodology for assigning levels of evidence to regimens.  We have taken a simplified approach to rating evidence, based on a three-color metric (red/yellow/green).  Of course, there are finer gradations of the quality of evidence so this simplified scheme should be taken with a grain of salt.
  
Please check back for completion of this page!
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We are currently collaborating on this list, which is a work in progress.  Criteria that may be considered:
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*Phase: I, II, III, IV
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*Interventional/observational
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**Cohort
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**Case-control
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**Cross-sectional study
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**Ecological study
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*Prospective/retrospective
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*Randomized, blind (single/double)
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*Compared against: placebo, standard of care
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*Superiority, non-inferiority, equivalence
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*Outcomes:
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**Overall survival
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**Progression-free survival
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**Quality of life/toxicity
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*Number of sites (single, regional, national, international)
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*Number of experimental arms
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Colors to be used:
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<span title="tooltip"
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style="background:#00CD00;
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padding:3px 6px 3px 6px;
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border-color:black;
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border-width:2px;
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border-style:solid;">Green box text</span>
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<span title="tooltip"
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style="background:#EEEE00;
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padding:3px 6px 3px 6px;
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border-color:black;
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border-width:2px;
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border-style:solid;">Yellow box text</span>
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<span title="tooltip"
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style="background:#ff0000;
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padding:3px 6px 3px 6px;
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border-color:black;
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border-width:2px;
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border-style:solid;">Red box text</span>

Revision as of 06:02, 2 November 2012

The purpose of this page is to create a reference to describe our methodology for assigning levels of evidence to regimens. We have taken a simplified approach to rating evidence, based on a three-color metric (red/yellow/green). Of course, there are finer gradations of the quality of evidence so this simplified scheme should be taken with a grain of salt.

We are currently collaborating on this list, which is a work in progress. Criteria that may be considered:

  • Phase: I, II, III, IV
  • Interventional/observational
    • Cohort
    • Case-control
    • Cross-sectional study
    • Ecological study
  • Prospective/retrospective
  • Randomized, blind (single/double)
  • Compared against: placebo, standard of care
  • Superiority, non-inferiority, equivalence
  • Outcomes:
    • Overall survival
    • Progression-free survival
    • Quality of life/toxicity
  • Number of sites (single, regional, national, international)
  • Number of experimental arms

Colors to be used: Green box text Yellow box text Red box text