Difference between revisions of "Carboplatin (Paraplatin)"
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==General information== | ==General information== | ||
Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.<ref name="insert">[http://packageinserts.bms.com/pi/pi_paraplatin.pdf Carboplatin (Paraplatin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/carboplatin.pdf Carboplatin (Paraplatin) package insert (locally hosted backup)]</ref> | Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.<ref name="insert">[http://packageinserts.bms.com/pi/pi_paraplatin.pdf Carboplatin (Paraplatin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/carboplatin.pdf Carboplatin (Paraplatin) package insert (locally hosted backup)]</ref> | ||
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| + | *[http://www.globalrph.com/carboplatin.htm Carboplatin AUC calculator]<ref>[http://www.globalrph.com/carboplatin.htm Carboplatin AUC calculator]</ref> | ||
| + | Route: IV | ||
<br>Extravasation: [[irritant]] | <br>Extravasation: [[irritant]] | ||
Revision as of 18:45, 16 August 2012
General information
Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.[1][2]
Route: IV
Extravasation: irritant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Patient drug information
- Carboplatin (Paraplatin) patient drug information (Chemocare)[4]
- Carboplatin (Paraplatin) patient drug information (UpToDate)[5]