Difference between revisions of "Example orders for 5-FU & low-dose Leucovorin (Mayo Clinic regimen - LDLV) in colon cancer"
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==5-FU & low-dose Leucovorin (Mayo Clinic regimen/LDLV)== | ==5-FU & low-dose Leucovorin (Mayo Clinic regimen/LDLV)== | ||
| − | Original | + | Original references may be found at [[Colon_cancer#Fluorouracil_.285-FU.29_.26_Folinic_acid_.28Leucovorin.29|5-FU & low-dose Leucovorin (Mayo Clinic regimen/LDLV) (adjuvant)]] & [[Colon_cancer#Fluorouracil_.285-FU.29_.26_Folinic_acid_.28Leucovorin.29_2|5-FU & low-dose Leucovorin (Mayo Clinic regimen/LDLV) (metastatic)]] |
===Example regimen #1=== | ===Example regimen #1=== | ||
Revision as of 16:36, 3 July 2012
Use of this site is subject to you reading and agreeing with the terms set forth in the disclaimer.
5-FU & low-dose Leucovorin (Mayo Clinic regimen/LDLV)
Original references may be found at 5-FU & low-dose Leucovorin (Mayo Clinic regimen/LDLV) (adjuvant) & 5-FU & low-dose Leucovorin (Mayo Clinic regimen/LDLV) (metastatic)
Example regimen #1
- Folinic acid (Leucovorin) 20 mg/m2 IV over 15-30 minutes on days 1-5, given first before 5-FU
- Fluorouracil (5-FU) 425 mg/m2 IV push on days 1-5, given after leucovorin
28-day cycles x 6 cycles for adjuvant therapy; in metastatic settings, given until progression of disease or unacceptable toxicity
Supportive medications:
- Prochlorperazine (Compazine) 10 mg PO 30 minutes prior to chemotherapy
Hydration:
- 500 ml NS at KVO rate as running IV for chemotherapy infusion. Give up to 500 ml NS.
Monitoring:
- Hold if ANC <1000 and platelets <100 and notify physician.