Difference between revisions of "All-trans retinoic acid (ATRA)"
Jump to navigation
Jump to search
(Created page with "==General information== Class/mechanism: <ref name="insert">[http://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20438s004lbl.pdf Tretinoin (Vesanoid) package insert]</ref><...") |
|||
| Line 1: | Line 1: | ||
| + | Also known as all-trans retinoic acid, or ATRA. | ||
| + | |||
==General information== | ==General information== | ||
| − | Class/mechanism: <ref name="insert">[http://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20438s004lbl.pdf Tretinoin (Vesanoid) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/tretinoin.pdf Tretinoin (Vesanoid) package insert (locally hosted backup)]</ref> | + | Class/mechanism: Retinoid, induces maturation/differentiation of [[Acute myeloid leukemia|acute promyelocytic leukemia (APL)]] cells. Exact mechanism unknown.<ref name="insert">[http://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20438s004lbl.pdf Tretinoin (Vesanoid) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/tretinoin.pdf Tretinoin (Vesanoid) package insert (locally hosted backup)]</ref> |
| − | <br>Route: | + | <br>Route: PO |
| − | <br>Extravasation: | + | <br>Extravasation: n/a |
| − | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the | + | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information<ref name="insert"></ref>. |
==Patient drug information== | ==Patient drug information== | ||
*[http://chemocare.com/bio/tretinoin.asp Tretinoin (Vesanoid) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/tretinoin.asp Tretinoin (Vesanoid) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/bio/tretinoin.asp Tretinoin (Vesanoid) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/tretinoin.asp Tretinoin (Vesanoid) patient drug information (Chemocare)]</ref> | ||
| − | *[http://www.uptodate.com/contents/tretinoin-patient-drug-information Tretinoin (Vesanoid) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/tretinoin-patient-drug-information Tretinoin (Vesanoid) patient drug information (UpToDate)]</ref> | + | *[http://www.uptodate.com/contents/all-trans-retinoic-acid-tretinoin-patient-drug-information Tretinoin (Vesanoid) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/all-trans-retinoic-acid-tretinoin-patient-drug-information Tretinoin (Vesanoid) patient drug information (UpToDate)]</ref> |
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 00:34, 26 February 2012
Also known as all-trans retinoic acid, or ATRA.
General information
Class/mechanism: Retinoid, induces maturation/differentiation of acute promyelocytic leukemia (APL) cells. Exact mechanism unknown.[1][2]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information[1].
Patient drug information
- Tretinoin (Vesanoid) patient drug information (Chemocare)[3]
- Tretinoin (Vesanoid) patient drug information (UpToDate)[4]