Difference between revisions of "Filgrastim (Neupogen)"
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| + | Also known as GCSF, G-CSF, or granulocyte colony stimulating factor. | ||
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==General information== | ==General information== | ||
Class/mechanism: Recombinant human granulocyte colony-stimulating factor (G-CSF). Binds to cell surface receptors on hematopoietic cells and stimulates proliferation‚ differentiation, and some end-cell functional activation.<ref name="insert">[http://pi.amgen.com/united_states/neupogen/neupogen_pi_hcp_english.pdf Filgrastim (Neupogen) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/filgrastim.pdf Filgrastim (Neupogen) package insert (locally hosted backup)]</ref> | Class/mechanism: Recombinant human granulocyte colony-stimulating factor (G-CSF). Binds to cell surface receptors on hematopoietic cells and stimulates proliferation‚ differentiation, and some end-cell functional activation.<ref name="insert">[http://pi.amgen.com/united_states/neupogen/neupogen_pi_hcp_english.pdf Filgrastim (Neupogen) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/filgrastim.pdf Filgrastim (Neupogen) package insert (locally hosted backup)]</ref> | ||
Revision as of 20:25, 24 February 2012
Also known as GCSF, G-CSF, or granulocyte colony stimulating factor.
General information
Class/mechanism: Recombinant human granulocyte colony-stimulating factor (G-CSF). Binds to cell surface receptors on hematopoietic cells and stimulates proliferation‚ differentiation, and some end-cell functional activation.[1][2]
Route: SC, IV
Extravasation: no known issues
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Filgrastim (Neupogen) patient drug information (Chemocare)[3]
- Filgrastim (Neupogen) patient drug information (UpToDate)[4]