Class/mechanism from NCI Drug Dictionary: A humanized IgG1 monoclonal antibody directed against the cell surface glycoprotein CD-38 with potential antineoplastic activity. Isatuximab specifically binds to CD38 on CD38-positive tumor cells.
Extravasation: no information
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Diseases for which it is used
History of changes in FDA indication
- 3/2/2020: Approved in combination with pomalidomide and dexamethasone for adult patients with multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor.
Also known as
- Code name: SAR-650984
- Generic name: isatuximab-irfc
- Brand name: Sarclisa