Factor XIII concentrate, human (Corifact)

General information

Class/mechanism: Human factor XIII; in the coagulation cascade, factor XIII is activated by thrombin (factor IIa) to factor XIIIa, which promotes cross-linking of fibrin. Factor XIIIa promotes stabilization of the fibrin clot by cross-linking alpha-2 plasmin inhibitor to the alpha chain of fibrin. Clinically used in patients with congenital factor XIII deficiency.[1][2][3]
Route: IV
Extravasation: no information

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Patient drug information

Also known as

  • Generic names: coagulation factor 13, FXIII
  • Brand name: Corifact

References