Palbociclib (Ibrance)

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Revision as of 01:18, 23 December 2014 by Jwarner (talk | contribs) (Created page with "==Mechanism of action== Orally bioavailable cyclin-dependent kinase 4/6 inhibitor. ==Preliminary data== # Vaughn DJ, Hwang W, Lal P, Rosen MA, Gallagher M, O'Dwyer PJ. Phase ...")
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Mechanism of action

Orally bioavailable cyclin-dependent kinase 4/6 inhibitor.

Preliminary data

  1. Vaughn DJ, Hwang W, Lal P, Rosen MA, Gallagher M, O'Dwyer PJ. Phase 2 trial of the cyclin-dependent kinase 4/6 inhibitor palbociclib in patients with retinoblastoma protein-expressing germ cell tumors. Cancer. 2014 Dec 18. [Epub ahead of print] link to original article PubMed