Therapeutic equivalents

This page is very much under construction at the moment.

Introduction

Generally speaking, prospective clinical trials are very specific in the drugs that they use in their evaluation. In clinical practice, one drug is often substituted for another, using the clinical concept of therapeutic equivalence. The purpose of this page is to gather various categories of therapeutic equivalence for general reference, and also to inform the HemOnc ontology. Please keep checking back as the page develops!

Categories of therapeutically equivalent drugs

Same drug, different route

(e.g., IV and SC daratumumab)

Combinations of agents

(e.g., Phesgo is combined pertuzumab & trastuzumab)

Pro-drugs

(e.g., capecitabine & 5-FU, although this is tricky because of LCV...)

Same class

(e.g., cisplatin and carboplatin)